Pathological manifestation of difference in washout pattern of adrenal hyperplasia on dynamic CT

Abstract

The key factors of washout pattern of AH on dynamic CT were CCR and TApre. The difference in constituent cell was associated with variability in APW of AH.

Relationship Among Tumor Attenuation Value of Pre-contrast Computed Tomography (CT), Washout Rate and Constituent Cells in Adrenal Adenoma: Proposition of a New Approach for Diagnosing Adrenal Adenoma on Dynamic CT

“…Previous reports have shown that lipid-rich AAs do not demonstrate washout patterns different from those of lipid-poor AAs (4,8,10). On the other hand, although adrenal hyperplasia closely resembles AA in histology and is composed of both clear cells and compact cells, the variability in washout rates has been reported to be associated with differences in constituent cells of adrenal hyperplasia (11). That is, the washout rate of adrenal hyperplasia increases as the clear cell ratio (CCR) decreases or as tumor attenuation value of the pre-contrastenhanced CT image (TApre) increases.…”