Pathologically Proved Nonspecific Interstitial Pneumonia: CT Pattern Analysis as Compared with Usual Interstitial Pneumonia CT Pattern

Sumikawa, Hiromitsu; Johkoh, Takeshi; Fujimoto, Kiminori; Arakawa, Hiroaki; Colby, Tomas V.; Fukuoka, Junya; Taniguchi, Hiroyuki; Kondoh, Yasuhiro; Kataoka, Kensuke; Ogura, Takashi; Baba, Tomohisa; Ichikado, Kazuya; Gyobu, Tomoko; Yanagawa, Masahiro; Honda, Osamu; Tomiyama, Noriyuki

doi:10.1148/radiol.14130853

Cited by 60 publications

(49 citation statements)

References 18 publications

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“…In this paper, however, no data are provided on the prognosis and evolution of these subjects, which, free of honeycomb by definition, may express a less advanced and/or less progressive IPF. As a matter of fact, Sumikawa et al [31] recently demonstrated that the outcome of patients with a possible UIP pattern at HRCT was significantly better than that of patients with a UIP pattern (mean survival 73.0 versus 33.5 months, respectively).…”

Section: Discussionmentioning

confidence: 99%

Idiopathic interstitial pneumonias: do HRCT criteria established by ATS/ERS/JRS/ALAT in 2011 predict disease progression and prognosis?

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Idiopathic interstitial pneumonias: do HRCT criteria established by ATS/ERS/JRS/ALAT in 2011 predict disease progression and prognosis?

et al. 2015

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“…Confidence of diagnosis specific to UIP was scored as inconsistent with UIP, indeterminate UIP, probable UIP, or UIP depending on the radiologists' opinion of the likelihood of the diagnosis based on imaging findings (Figs 1-4). [16][17][18][19] A UIP pattern was defined as basilar and peripheral preponderant fibrosis with honeycombing and absence of features to suggest another alternative diagnosis. Probable UIP was defined as basilar and peripheral preponderant fibrosis with little or no honeycombing and absence of features to suggest another alternative diagnosis.…”

Section: Ct Imaging Evaluationmentioning

confidence: 99%

CT Imaging Phenotypes of Pulmonary Fibrosis in the MUC5B Promoter Site Polymorphism

Chung

Peljto

Chawla

et al. 2016

Chest

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“…Another research group reported their comparison between CT patterns and pathologic diagnoses: Sumikawa et al noted that 21 of 56 (38%) patients with an NSIP pattern at CT were classified as having pathologic UIP; however, the sequential changes in HRCT findings of these patients were not described in that study [17]. Though several past studies suggested that wider honeycombing is one of the HRCT findings suggesting the diagnosis of IPF [18], [19] and recent IPF guidelines might set a high value on HRCT patterns to diagnose IPF, honeycombing on HRCT may not be essential for diagnosing IPF.…”

Section: Discussionmentioning

confidence: 94%

Clinical course and changes in high-resolution computed tomography findings in patients with idiopathic pulmonary fibrosis without honeycombing

Yamauchi

Bando

Baba

et al. 2015

1.5 Diffuse Parenchymal Lung Disease

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Some patients with idiopathic pulmonary fibrosis (IPF) do not have honeycombing on highresolution computed tomography (HRCT) at their initial evaluation. The clinical course and sequential changes in HRCT findings in these patients are not fully understood. We reviewed the cases of 43 patients with IPF without honeycombing on initial HRCT from institutions throughout Japan. All patients were diagnosed with IPF based on a surgical lung biopsy. Multidisciplinary discussions were held five times between 2011 and 2014, to exclude alternative etiologies. We evaluated the sequential changes in HRCT findings in 30 patients with IPF. We classified these 30 patients into three groups based on their HRCT patterns and clarified the clinical characteristics and prognosis among the groups. The patterns of all 30 patients on initial HRCT corresponded to a possible usual interstitial pneumonia (UIP) pattern which was described in the 2011 International Statement. On long-term follow-up (71.0±38.7 standard deviation [SD] months), honeycombing was seen in 16 patients (53%, the HoneyCo group); traction bronchiectasis or cysts without honeycombing was observed in 12 patients (40%, the NoHoneyCo group), and two patients showed no interval change (7%, the NoChange group) on HRCT. The mean survival periods of the HoneyCo and NoHoneyCo groups were 67.1 and 61.2 months, respectively (p = 0.76). There are some patients with IPF whose conditions chronically progress without PLOS ONE |

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Pathologically Proved Nonspecific Interstitial Pneumonia: CT Pattern Analysis as Compared with Usual Interstitial Pneumonia CT Pattern

Abstract: CT pattern in patients with pathologic NSIP is more uniform than that in patients with pathologic UIP, and CT NSIP pattern is associated with better patient outcome than is CT UIP pattern.

Cited by 60 publications

References 18 publications

Idiopathic interstitial pneumonias: do HRCT criteria established by ATS/ERS/JRS/ALAT in 2011 predict disease progression and prognosis?

Idiopathic interstitial pneumonias: do HRCT criteria established by ATS/ERS/JRS/ALAT in 2011 predict disease progression and prognosis?

CT Imaging Phenotypes of Pulmonary Fibrosis in the MUC5B Promoter Site Polymorphism

Clinical course and changes in high-resolution computed tomography findings in patients with idiopathic pulmonary fibrosis without honeycombing

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