Pathologisch-anatomische und klinisch-röntgenologische Studien über die sogenannten Wachstumslinien

Wolf, H.; Psenner, L.

doi:10.1055/s-0029-1212257

Cited by 6 publications

(1 citation statement)

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“…The reaction possi bilities of the bone, like other organs, are limited. The transverse lines are found above all in places of greatest growth intensity, particularly the proximal end of the tibia and the distal end of the femur [12], Soft lines that do not cover the whole width of the diaphysis are not regarded as def initely pathological [8]; they have not been taken into account.…”

Section: Discussionmentioning

confidence: 99%

Ossification Disturbances in Children under Antiepileptic Treatment

Lässker¹,

Degen²,

Köthe³

1971

Stereotact Funct Neurosurg

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After one patient had shown rachitic bone changes and analogous chemical deviations in the blood after long-term antiepileptic treatment, 51 children were examined. They had undergone anti-convulsive treatment at least for 3 years. X-rays of the skull, knee, hand-joints and determinations of serum calcium, phosphate and alkaline phosphatase have been carried out. Another case of rickets could not be found. 13 patients (25.5 %) have shown ossification disturbances consisting in increased number and intensity of transverse lines of the metaphyses. These 13 patients had had more severe cerebral damage than those without pathological X-ray findings. They had received higher doses and always a combination of at least 2 preparations. Biochemical alterations, however, could not be found in any case. The ''antiepileptic rickets'' disappeared after vitamin D administration, after which the child''s state became much better.

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Section: Discussionmentioning

confidence: 99%