Pathology and prognosis of gastric carcinoma

Characteristics of Synchronous Cancers in Gastric Cancer Patients

“…As the incidence of cancer increases with age, it appears likely that the actual incidence of synchronous cancer in elderly gastric cancer patients may be somewhat higher than expected. A high incidence of differentiated gastric cancer was found in this study, and this appears to be associated with the high incidence of early-stage gastric cancer (13,14).…”

Risk Factors of Survival and Surgical Treatment for Advanced Gastric Cancer with Large Tumor Size

“…Adachi et al reported that patients with gastric cancer of poorly differentiated pathological type were distinguished by their female predomination, infiltrative gross type, serosal invasion, lymph node metastasis, peritoneal dissemination, and advanced stage. 11 Although the pathological type was not an independent factor for survival under multivariate analysis, undifferentiated histological type predomination may play some role in the malignant behavior of larger tumors.…”

Crocodile choline fromCrocodylus siamensisinduces apoptosis of human gastric cancer

“…Furthermore, the cells of lower differentiation level seemed to be more sensitive to CCL, and the poorly differentiated BGC823 cells were found to be the most sensitive one, with the lowest IC 50 value. However, many researchers [17][18][19] have claimed that patients with the poorly differentiated type had more significant invasion, much more lymph node involvement, and more advanced stage than patients with the well-differentiated type, and had more aggressive features, poorer prognosis, and lower survival rates. Given this, poorly differentiated BGC823 cell line was used for further study.…”