Pathology features and the results of treatment of two cases of posterior choroidal leiomyoma

Zhou, Nan; Wei, Wenbin; Xu, Xiaolin

doi:10.1186/s12886-020-01445-6

Cited by 2 publications

(9 citation statements)

References 9 publications

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“…Koroidal leiomiyomlar benign karakterde; ancak özellikle amelanotik koroidal melanomdan ayırıcı tanısının yapılması gereken tümörlerdir. 5 Literatürdeki en geniş uveal leiomiyom vaka serisi Shields ve ark. 9 tarafından 1994 yılında yayınlanan yedi olguluk seridir.…”

Section: Koroidal Miyojenik Tümörlerunclassified

“…4,9 Koroidal leiomiyomlar yavaş büyür, metastaz yapmaz ve sistemik olarak benign karakterdedirler; ancak lokal olarak destrüktif özellik gösterirler. 4,5 Hastalarda görmeyi tehdit edecek düzeyde büyük kitle lezyonu ve eksudatif dekolman görülebilir. 9 Bu sebeple klinik muayene ile leiomiyomların ayırıcı tanısı mümkün olmayıp kesin tanı ancak histopatoloji ile yapılabilir.…”

Section: Koroidal Leiomiyomunclassified

“…Literatürdeki olguların büyük kısmında eksudatif retina dekolmanının eşlik ettiği bildirilmiştir. 5,9,74 Sarı renkli subretinal lipid eksudasyonları da bazı olgularda bildirilmiştir. 9 Nadir olarak tümörün büyümesi ile skleral incelme ve ektazi ile ekstraskleral uzanım görülebilir.…”

Section: Tanıunclassified

“…Erken fazlarda hipofloresans, geç fazlarda ise yüzeyden yaygın sızıntı ile hiperfloresan görünüm mevcuttur. 5 Koroidal melanomun aksine leiomiyom olgularında suprauveal yerleşim nedeniyle koroidal vasküler yapılar normal paternde izlenir. 9 Ultrasonik biyomikroskopi (UBM) koroidal leiomiyomların periferal koroidal yerleşimleri nedeniyle özellikle değerlidir.…”

Section: Tanıunclassified

“…CURRENT RETINA -GÜNCEL RETINA tadır. 5 Literatürde bildirilmiş primer koroidal leiomiyosarkom ve rabdomiyosarkom olgusu olmamakla birlikte koroidal metastatik leiomiyosarkom olguları mevcuttur. [6][7][8] Osseoz tümörlerde çoğu olguda detaylı muayene ve multimodal görüntüleme yöntemleriyle klinik tanı konulabilmekteyken miyojenik tümörlerde ise ayırıcı tanı doku tanısıyla mümkün olmaktadır.…”

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Osseous and Myogenic Tumors of the Choroid

SARIGÜL SEZENÖZ,

KARABAY

2023

CRJ

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Myogenic and osseous tumors of the choroid are extremely rare clinical manifestations. The most common osseous choroidal tumor is choroidal osteoma, and the most common myogenic choroidal tumor is choroidal leiomyoma. Other common osseous lesions are listed as sclerochoroidal calcification and ossified choroidal hemangioma. It is of great importance to distinguish these lesions from malignant tumors, especially malignant melanoma. Multimodal imaging methods and tissue diagnosis with biopsy and immunohistochemical markers in myogenic tumors have an important place in the diagnosis. Although it is known that these lesions are systemically benign, they can threaten vision as a result of local mass effect and complications. Since some osseous tumors may accompany systemic metabolic disorders, systemic screening should be performed in necessary cases. Although rare, metastatic choroidal leiomyosarcoma cases have been described. In this case, it is important to diagnose the tumor quickly and accurately with a good anamnesis and tissue diagnosis, and to plan the appropriate treatment considering the sensitivity of the primary tumor.

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Section: Koroidal Miyojenik Tümörlerunclassified

Section: Koroidal Leiomiyomunclassified

Section: Tanıunclassified

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Osseous and Myogenic Tumors of the Choroid

SARIGÜL SEZENÖZ,

KARABAY

2023

CRJ

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Posterior choroidal leiomyoma: new findings from a case and literature review

Pan

Chen

et al. 2023

Int J Ophthalmol

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Posterior choroidal leiomyoma is a sporadic, rare benign tumor that is always confused with anaplastic melanoma. Here we report a case and provide a review. Most of the preoperative findings in our case were suggestive of malignant choroidal melanoma. However, the contrast enhanced ultrasound (CEUS) suggested a benign hemangioma. In summary, the posterior choroidal leiomyomas were yellowish-white in color and most commonly located in the temporal quadrant of the fundus (11/15). They were more frequent in Asians (13/16), the prevalence was almost equal in males and females (9:7), with a mean age of 35y. Microscopically, the tumor typically showed spindle cell bundles and nonmitotic ovoid nuclei arranged in intersecting fascicles. Vitrectomy is now a popular treatment option and definitive diagnosis can be made after immunohistochemistry. Finally, some summarized features of this tumor differ from those previously described. These may help in the diagnosis of posterior choroidal leiomyoma and differentiation from malignant melanoma.

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Pathology features and the results of treatment of two cases of posterior choroidal leiomyoma

Cited by 2 publications

References 9 publications

Osseous and Myogenic Tumors of the Choroid

Osseous and Myogenic Tumors of the Choroid

Posterior choroidal leiomyoma: new findings from a case and literature review

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