Pathology of Intraocular Lenses in 33 Eyes Examined Postmortem

McDonnell, Peter J.; Green, W. Richard; Maumenee, A. Edward; Iliff, W. Jackson

doi:10.1016/s0161-6420(83)34558-9

Cited by 116 publications

(25 citation statements)

References 31 publications

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“…These methods have fewer incidences of complications than intracapsular extraction with anterior chamber lenses [1][2][3][4][5]. These complications include posterior capsular opacification [6--8], malpositioning of the implant [9][10][11], pseudophakic retinal detachment [12], corneal endothelial cell loss [13][14], cystoid macular edema [15] and postoperative glaucoma [16][17].…”

Section: Introductionmentioning

confidence: 99%

Pupil abnormalities on the first postoperative day after cataract surgery

1997

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Most, if not all, ophthalmologists strive to achieve a round pupil after cataract surgery with posterior chamber lens implantation. The presence of pupil abnormalities and iris modifications is cosmetically undesirable and may affect the quality of postoperative vision. The pupillary motility may be changed which will in turn affect both pupillary light reflexes and pupillary dilatation during fundus examination. In this paper, we prospectively studied 2 groups of patients who underwent uncomplicated cataract surgery with posterior chamber lens implantation; 100 patients who had planned extracapsular cataract extraction (ECCE), and 130 patients who underwent phacoemulsification. On the first postoperative day, we found a 16% rate of pupil abnormalities in the group which underwent ECCE surgery while only 5.3% of the phacoemulsification group had pupil abnormalities. There were different causes in which the two groups. The most common cause of pupil abnormality after ECCE was due to iris sphincter rupture, whereas the most common cause after phacoemulsification was due to iris trauma during phacoemulsification. These pupil abnormalities are the direct consequence of factors in surgery and we suggest ways to minimize the occurrence of such abnormalities in cataract surgery.

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Section: Introductionmentioning

confidence: 99%

Pupil abnormalities on the first postoperative day after cataract surgery

1997

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“…The overall design of this type of IOL would provide better stability within the eye. [6][7][8][9][10] showed that compared with iris-clip IOLs, iridocapsular IOLs had a markedly decreased rate of corneal bullous keratopathy. However, some studies note that if one or both loops were placed outside the capsular bag, it would essentially convert the iridocapsular IOL to an iris-supported IOL, eventually leading to pathology of the iris and supporting tissues.…”

Section: Discussionmentioning

confidence: 99%

“…The optical component of this IOL remained in front of the iris, but the haptics were inserted into the residual capsular bag after extracapsular extraction or placed in the iridocapsular cleft, where iridocapsular adhesions were expected to embed them, providing stability. [6][7][8][9][10] We recently had the opportunity to perform pathological analyses of an enucleated eye, obtained postmortem, that had a 2-loop iridocapsular IOL. To our knowledge, this is the longest reported follow-up describing the long-term pathological results of this type of IOL in the human eye.…”

mentioning

confidence: 99%

Long-term pathological follow-up of 2-loop iridocapsular intraocular lens

Burrow

Werner

Maddula

et al. 2011

Journal of Cataract and Refractive Surgery

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We analyzed an enucleated postmortem eye from an 86-year-old donor who had a 2-loop iridocapsular intraocular lens (IOL) that had been implanted at least 30 years earlier. High-frequency ultrasound showed a relatively well-centered iris-supported optic in front of the pupil. Gross and light microscopic analyses of the eye and the IOL showed loop fixation outside the capsular bag remnants, a thickened cornea, mild attenuation of the corneal endothelium, multiple areas of iris trauma secondary to haptic abrasion, fragments of iris tissue attached to the haptics, as well as pigment dispersion within the eye with pigmented epithelial cells attached to the IOL haptics. Histopathological examination of the posterior segment was unremarkable.

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“…Histological studies have shown erosion of the ciliary body and iris when the supported loops of posterior chamber lenses were lo cated outside the capsular bag [McDonnell et al, 1983a;Apple et al. 1984aApple et al.…”

Section: Discussionmentioning

confidence: 99%

Posterior Chamber Lens Implantation: Histopathological Report of a Successful Case

et al. 1988

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Using electron microscopy, we examined an eye obtained at autopsy in which a C-loop intraocular lens had been implanted into the posterior chamber 2 years and 4 months prior to the patient’s death. The lens was affixed with the superior loop outside the capsular bag and the inferior loop within the capsular bag. The two ciliary epithelial layers to which the superior loop was attached were thinned; the pigmented epithelial layer was completely absent and the nonpigmented epithelial layer was disrupted, suggesting breakdown of the blood-aqueous barrier. Proliferating lens epithelial cells, basement membrane-like material, collagen fibers and microfibrils were seen surrounding the inferior loop. The lens capsule, the zonular fibers and the ciliary epithelium adjacent to the inferior loop showed no pathological changes.

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Pathology of Intraocular Lenses in 33 Eyes Examined Postmortem

Cited by 116 publications

References 31 publications

Pupil abnormalities on the first postoperative day after cataract surgery

Pupil abnormalities on the first postoperative day after cataract surgery

Long-term pathological follow-up of 2-loop iridocapsular intraocular lens

Posterior Chamber Lens Implantation: Histopathological Report of a Successful Case

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