Pathology of Melanocytic Skin Tumors

Clemente, Claudio; Mihm, Martín C.

doi:10.1007/978-1-4614-7357-2_7

Cited by 2 publications

(2 citation statements)

References 68 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Black-skinned race whom suffer from skin cancer, having a higher morbidity and mortality than other races (Abbas F, Kumar V., 2007). The incidence of non melanoma skin malignancies on white-skinned race was 232,6/100, while on black-skinned race was 3,4/100 (Lebolt.P.E. et al, 2005;Elder D et al, 2005).…”

Section: Disscussionmentioning

confidence: 99%

See 1 more Smart Citation

Pattern and Frequency of Skin Malignancies at Laboratory of Pathology Anatomy Dr. Kariadi General Hospital in 2008-2009

Susilorini

Sadhana²,

Widjaya³

2015

Sains Med. J. Kedokt. dan Kesehat.

View full text Add to dashboard Cite

Introduction: A periodical database is important including for skin cancer. Periodical registration is needed to acknowledge changes in pattern and frequencies of skin lesion. Objective: The purpose of this study was to describe the pattern and the frequency of skin lesion in RSUD Kariadi.Method: A cross-sectional study was conducted through analysis of the medical records of patients diagnosed skin lesion in the pathology labolatory of RSUD Kariadi between 2008 and 2009. The variables were secondary data including age, gender, specimen area, dan histopathology diagnosis. Data was choosen by consecutive sampling from 381 medical records of skin tissues examined at laboratorium of pathology anatomy of Dr. Kariadi general hospital during 2008-2009.Result: 381 cases were recorded comprising of 246 (65%) neoplastic and 135 (35%) non neoplastic lesion. 120 patients presented with skin cancer, and 126 with benign skin lesion. Most malignancy was observed among female patients (62.5%) on age catagory of 15-39 (65%). The most common lesion was basal cell carcinoma (48.3%) followed by squamous cell carcinoma (33.3%), malignant melanoma (10%), skin appendix carcinoma (2.5%), other malignancies (4.9%).Conclusion: the most common malignancies in Dr. Kariadi general hospital before 2008 was similar to data from 13 laboratory of pathology anatomy in Indonesia, which is squamous cell carcinoma.

show abstract

Section: Disscussionmentioning

confidence: 99%

“…In Australia, the skin cancer accounts for over than 50% all malignancies. Thirteen million white non-Hispanic living in the US at the beginning of 2007 had at least one non melanoma skin cancer, typically diagnosed as basal cell carcinoma (BCC) or squamous cell carcinoma (SCC) (Lebolt.P.E., et al, 2005;Elder et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Pattern and Frequency of Skin Malignancies at Laboratory of Pathology Anatomy Dr. Kariadi General Hospital in 2008-2009

Susilorini

Sadhana²,

Widjaya³

2015

Sains Med. J. Kedokt. dan Kesehat.

View full text Add to dashboard Cite

show abstract

Reticulin immunostaining revisited

Torres

Kazlouskaya

Parikh

et al. 2016

Indian Dermatol Online J

View full text Add to dashboard Cite

Introduction:Reticulin staining has been suggested as an inexpensive tool in the differential diagnosis of melanoma versus benign nevi. In the present study, reticulin immunostaining patterns in malignant melanomas, benign intradermal nevi, and blue nevi were observed. The concordance in evaluation of the pattern between observers was also done.Materials and Methods:A retrospective search was performed in the computer database of the Ackerman Academy of Dermatopathology for “melanoma,” “melanocytic nevus,” and “blue nevus”. Fifty-six melanomas (30 of nodular subtype and 26 of superficial spreading subtype), 54 benign compound nevi, and 27 blue nevi were selected for the study. Patterns of reticulin staining in the dermis and the basement membrane in these melanocytic lesions were evaluated and the concordance between the two groups of authors was assessed. Statistical evaluation was performed with the Statistica® 10 program, Tulsa, OK. Concordance of the pattern evaluation was evaluated using Cohen's kappa coefficient.Results:Melanomas show a variable basement membrane pattern some of which show flat, thin and smooth pattern. Benign nevi almost never showed this flat pattern at the basement membrane zone. In the dermis, melanomas showed reticulin fibers surrounding groups of melanocytic cells while nevi predominantly had reticulin fibers around individual cells. There was greater agreement in evaluating the dermal component compared to the basement membrane pattern.Conclusion:The dermal reticulin staining pattern may be of some value in the diagnosis of melanocytic lesions, but poor concordance in evaluation of the basement membrane zone pattern limits its usefulness.

show abstract

Pathology of Melanocytic Skin Tumors

Cited by 2 publications

References 68 publications

Pattern and Frequency of Skin Malignancies at Laboratory of Pathology Anatomy Dr. Kariadi General Hospital in 2008-2009

Pattern and Frequency of Skin Malignancies at Laboratory of Pathology Anatomy Dr. Kariadi General Hospital in 2008-2009

Reticulin immunostaining revisited

Contact Info

Product

Resources

About