Pathology of Renal and Adrenal Neoplasms

Leder, L.-D.; Richter, Hans

doi:10.1007/978-3-642-71207-4_1

Cited by 3 publications

(2 citation statements)

References 311 publications

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“…The histologic similarity to RCC and the attempts to differentiate them from their malignant counterparts remain the subject of controversy among pathologists. The guidelines used in the past, in which tumors measuring less than 3 cm are considered adenomas, have been abandoned, and today only extremely small tumors are labeled adenoma [Leder et al, 1979]. This distinction is still arbitrary, and an answer to the question “Is this tumor adenoma or RCC?” can be found in the cytogenetic studies performed on several adenomas [Sandberg and Turc‐Carel, 1987; Dal Cin et al, 1989].…”

Section: Introductionmentioning

confidence: 99%

Renal cancer: Cytogenetic and molecular genetic aspects

Meloni‐Ehrig

2002

Am. J. Med. Genet.

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To date, much progress has been made in the fields of cytogenetics and molecular genetics of renal tumors. The previous and recent findings have delineated the characteristics of the various tumors, particularly the cytogenetic and molecular differences that exist between papillary and nonpapillary clear cell renal cell carcinomas (RCCs). At the same time, new cytogenetic subtypes have emerged [e.g., t(X;1)] in subtypes of RCC, while in others (e.g., Wilms tumors) several new cytogenetic abnormalities and consequent molecular involvement have been found. In addition to Wilms tumor, papillary RCC, and clear-cell RCC, cytogenetic and fluorescence in situ hybridization analyses have been performed on several other tumors of the kidney, including chromophobic carcinoma, metanephric adenoma, collecting duct carcinoma, transitional cell carcinoma, congenital mesoblastic nephroma, and malignant rhabdoid tumors of the kidney. This review is therefore intended to present a concise update on the cytogenetic and molecular data on renal tumors, focusing mainly on the clinical usefulness of the findings reported in the literature.

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Section: Introductionmentioning

confidence: 99%

Renal cancer: Cytogenetic and molecular genetic aspects

Meloni‐Ehrig

2002

Am. J. Med. Genet.

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“…Angiomyolipoma, a benign mixed mesenchymal tu mor that mainly occurs in the kidney, has been classically regarded as an example of choristoma [1], Up to 80% of the patients with tuberous sclerosis develop renal angiomyolipomas, although it is a rather uncommon neoplasm in the general population [2][3][4], Extrarenal location is even more infrequent [5]. We present a further patient with an extrarenal angiomyolipoma arising in the peri nephric space.…”

Section: Introductionmentioning

confidence: 99%

Extrarenal Retroperitoneal Angiomyolipoma

Angulo

López²,

Carnicero³

et al. 1994

Urol Int

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Retrospective Ultrasonographic Evaluation of Adrenal Lesions in 26 Dogs

Besso

Penninck

Gliatto

1997

Vet Radiology Ultrasound

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A review was performed of ultrasonographic findings in 26 dogs with confirmed adrenal lesions. Adrenal shape, size, echogenicity, laterality, and the presence of vascular invasion were evaluated. Histopathologic diagnoses were obtained in all dogs. Adrenal lesions were confirmed as pheochromocytomas (9), adenocarcinomas (6), a poorly differentiated blastoma (1), bilateral adrenal metastases of a carcinoma (1), adenomas--one of which was bilateral--(4) and hyperplasia (6). Size and shape were extremely variable and not specific to lesion type. There was a tendency for pheochromocytomas (7), adenocarcinomas (5) and poorly differentiated blastoma (1) to be rounded masses. Adenomas (4), hyperplasia (7) and adrenal metastases (2) presented predominantly as nodules. No specificity in echogenicity was noted. Mineralization and bilaterality were present in both benign and malignant lesions. Vascular extension or the presence of a thrombus were suggestive but not specific signs of malignancy. Based on our preliminary study, ultrasonography is an effective method for localizing adrenal lesions and is helpful in assessing their extension. However, no definitive differentiation between benign and malignant lesions was possible using ultrasonographic criteria alone.

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Pathology of Renal and Adrenal Neoplasms

Cited by 3 publications

References 311 publications

Renal cancer: Cytogenetic and molecular genetic aspects

Renal cancer: Cytogenetic and molecular genetic aspects

Extrarenal Retroperitoneal Angiomyolipoma

Retrospective Ultrasonographic Evaluation of Adrenal Lesions in 26 Dogs

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