2009
DOI: 10.1007/s00381-009-1054-9
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Pathomechanisms and treatment of pediatric aneurysms

Abstract: Pediatric aneurysms are rare diseases distinct from classical adult aneurysms and therefore require different treatment strategies. Apart from saccular aneurysms that are more commonly found in older children, three major pathomechanisms may be encountered: trauma, infection, and dissection. The posterior circulation and more distal locations are more commonly encountered in children compared to adults, and there is an overall male predominance. Clinical findings are not only confined to subarachnoid hemorrhag… Show more

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Cited by 107 publications
(119 citation statements)
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“…Discovery of UIA is linked to presentations with seizures, non-SAH-related headaches, or another neurological deficit approximately 40 % of the time [3,6]. Dissecting aneurysms in particular can lead to mass effect, hemorrhage, or ischemia [6]. There are few reports of incidentally found UIA in children during routine autopsy studies [6,8].…”
Section: Discussionmentioning
confidence: 99%
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“…Discovery of UIA is linked to presentations with seizures, non-SAH-related headaches, or another neurological deficit approximately 40 % of the time [3,6]. Dissecting aneurysms in particular can lead to mass effect, hemorrhage, or ischemia [6]. There are few reports of incidentally found UIA in children during routine autopsy studies [6,8].…”
Section: Discussionmentioning
confidence: 99%
“…Dissecting aneurysms in particular can lead to mass effect, hemorrhage, or ischemia [6]. There are few reports of incidentally found UIA in children during routine autopsy studies [6,8]. Given that a majority of pediatric UIAs are symptomatic, treatment is important in order to prevent aneurysm rupture or worsening of symptoms due to UIA.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…12 Dissecting aneurysms in children are the most common type and can cause infarction, hemorrhage, or mass effect. 5 Spontaneous dissecting aneurysms of the MCA in children often cause ischemia, but these lesions also can rupture. 8 In a multicenter report of 22 pediatric aneurysms, Proust et al 9 noted that the locations of pediatric intracranial aneurysms differed from the most common sites in adults: 36.4% of pediatric aneurysms were located at the ICA bifurcation, a relatively rare site for aneurysms in adults.…”
Section: Discussionmentioning
confidence: 99%
“…4 Giant PTAs represent a therapeutic challenge and, ideally, complete surgical removal or trapping of the aneurysm (which may necessitate bypass surgery) was deemed to be the treatment of choice. 8 Because some dissecting aneurysms initially may be asymptomatic, 8,16 it may be hypothesized that some patients with chronic dissecting aneurysms may only present with symptoms caused by mass effect after their dissecting aneurysm has evolved into a PTA. Given this presumed pathomechanism, it may be more accurate to refer to these lesions as aneurysms with intramural hematoma instead of "partially thrombosed" aneurysms.…”
Section: Operation and Postoperative Coursementioning
confidence: 99%