Pathophysiologie, Diagnostik und Therapie von chronischem Husten: Neuronale Reflexe und Antitussiva

Dinh, QT; Heck, Sebastian; Le, Duc-Dung; Bals, R; Welte, Tobias

doi:10.1055/s-0032-1309694

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Methylxanthines In Cough Management1

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2016

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“…The reflex impulse arrives to the cerebral cough center, located in the upper brain stem and pons, via the vagus nerve. Vagus, phrenic, and spinal motor nerves constitute the efferent pathway arriving to diaphragm, abdominal wall and expiratory muscles and generate a coordinated response [96].…”

Section: Methylxanthines In Cough Managementmentioning

confidence: 99%

The potential of methylxanthine-based therapies in pediatric respiratory tract diseases

Oñatibia-Astibia¹,

Martínez‐Pinilla

Franco

2016

Respiratory Medicine

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Caffeine, theophylline and theobromine are the most known methylxanthines as they are present in coffee, tea and/or chocolate. In the last decades, a huge experimental effort has been devoted to get insight into the variety of actions that these compounds exert in humans. From such knowledge it is known that methylxanthines have a great potential in prevention, therapy and/or management of a variety of diseases. The benefits of methylxanthine-based therapies in the apnea of prematurity and their translational potential in pediatric affections of the respiratory tract are here presented.

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Section: Methylxanthines In Cough Managementmentioning

confidence: 99%