Pathophysiology of Vibration Disease

Matoba, Tsunetaka; Kusumoto, Hisao; Kuwahara, Hiroshi; Inanaga, Kazutoyo; Oshima, Minako; Takamatsu, Makoto; Esmu, Koji

doi:10.1539/joh1959.17.11

Cited by 11 publications

(16 citation statements)

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“…Railroad engineers are exposed to vibration while working in moving locomotives (41). Some authors have claimed that even local vibration may cause pathological changes in the spinal cord and encephalopathy (10,19,22,23,42), and EEG abnormalities in the form of reduced amplitude or reduced reactivity have been connected to later stages of vibration syndrome. However, it is unlikely that whole body vibration would be thE' etiologic factor for the EEG ab-312 II.…”

Section: Discussionmentioning

confidence: 99%

Neurophysiological effects of long-term exposure to a mixture of organic solvents.

Seppäläinen¹,

Husman²,

Martenson³

1978

Scand J Work Environ Health

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effects of long-term exposure to a mixture of organic solvents. Scand. j. work environ. & health 4 (1978) [304][305][306][307][308][309][310][311][312][313][314]. Neurophysiological effects of long-term exposure to a mixture of organic solvents was studied among 102 car painters from 27 car repair garages in Helsinki. The reference group consisted of 102 age-matched railroad engineers from the Finnish State Railways. The mean age was 35 years and the exposure time ranged from 1 to 40 years (mean 14.8, SD 8.5). According to measurements the mean concentration of the solvent mixture was relatively low in the garages, namely, 31.8 % of the Finnish threshold limit value (TLV), the range of separate components varying from 4 to 212 % of the respective TLVs. The main components of about 20 organic solvents of the mixture were toluene, xylene, butyl acetate and white spirit. Electroencephalograms (EEGs) of all the 102 exposed and 102 nonexposed subjects were studied, but electroneuromyographic measurements were made of only 59 car painters and 53 referents with a similar age distribution. Motor (MCV and CVSF) and sensory conduction (SCV) velocities, as well as motor distal latencies, were recorded from nerves in the upper and lower extremities. Abnormal EEGs were encountered in 32 car painters and 37 referents. The frequency of abnormal EEGs was in both groups higher than expected on the basis of EEG literature (about 10 0 /0). Twenty-six car painters had a complex of four common symptoms of disturbances in the central nervous system; the same symptom complex was found in 12 engineers. Forty-six percent of the car painters with this symptom complex had an abnormal EEG, while only 26 Ofo of those without this symptom complex had an abnormal EEG. Railroad engineers did not show such a tendency. Abnormally slow MCVs or SCVs and/or prolonged motor distal latencies were found in 12 of the 59 car painters but in none of the 53 engineers studied. Other authors have stressed that many solvents primarily cause neuropathy, while objective signs of central nervous involvement have been minor, if any. Our findings are similar; they showed slight positive signs of slowed nerve conduction velocities among the car painters and no increase in EEG abnormalities in comparison to the reference group of railroad engineers.

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Section: Discussionmentioning

confidence: 99%

Neurophysiological effects of long-term exposure to a mixture of organic solvents.

Seppäläinen¹,

Husman²,

Martenson³

1978

Scand J Work Environ Health

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show abstract

“…However, insomnia, as are many of the proposed "autonomic symptoms," is a frequent complaint in modern society, where about 30-40 % suffer from transient insomnia and about 10-15 % from permanent sleep disturbances (118). Furthermore, as indicated by Matoba and co-workers (67,70), the causative factor is not evident from the prevalence data, since temporary conflicts in daily life (118) may interfere with the quality of life perceived. A more comprehensive analysis of the various factors involved is called for in the case of vibration-exposed workers.…”

Section: A Central or A Peripheral Disorder?mentioning

confidence: 94%

“…Consequently, some of the literature treats vibration syndrome as a disorder entity which is thought to originate from continuous reflex activation of the hypothalamic autonomic centers, causing a maladaptation response (30,31,67,70) . The disorder is said to comprise several stages which, when combined, correspond to the classification system of AndreevaGalanina (30,31).…”

Section: A Central or A Peripheral Disorder?mentioning

confidence: 99%

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Clinical aspects of the hand-arm vibration syndrome. A review.

Pyykkö¹

1986

Scand J Work Environ Health

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“…Vibration disease induced by the mechanical vibration has been reported to impair not only the functions of the peripheral nervous system and circulatory system and mobility in the upper extremities, but also the function of the central nervous system (Matoba et al 1974). The main causes of this disease are presumably noises and vibrations generated by a vibrating tool and coldness in the environment.…”

mentioning

confidence: 99%