Background
Several studies have been conducted on the effect of interventions on the detection of depression in primary healthcare (PHC). Systematic reviews have also been done on the effectiveness of separate interventions to improve clinicians’ recognition of depression in the PHC setting. However, systematic reviews are not done on the comparative effectiveness of several interventions together. This study, therefore, aimed at synthesizing the global evidence on the effectiveness of interventions to improve the detection of depression in primary healthcare.
Methods
We searched PubMed, Embase, PsycINFO, Web of Science, Cochrane Database of Systematic Reviews, Global Index Medicus, African Index Medicus and African Journals Online, from the inception of the databases to until the 4th week of April 2020. We also searched references of the included articles. We included randomized controlled trials, cluster randomized trials or quasi-experimental studies, which evaluated the effectiveness of an intervention to improve detection of depression in the PHC setting. Two of the review authors independently extracted data from the included studies. The methodological quality of the included studies was assessed using the Assessment Tool for Quantitative Studies developed by the Effective Public Health Practice Project. The protocol for the review was registered on PROSPERO (CRD42020166291).
Results
Of 23,305 records identified, we included 58 articles in the review. Diverse types of interventions were evaluated to improve clinician diagnosis of depression in the PHC setting. Interventions related to implementation of guidelines, screening with feedback, educational interventions which incorporated active learning and clinical practice, and disclosure of screening results were found to be mostly effective. Interventions which combined education, screening and feedback were particularly more effective. Most of the included studies were weak or moderate in their methodological quality.
Conclusions
Our review indicates that implementation of a single type of intervention does not improve the detection of depression in PHC. Combining aspects of each type of intervention which are more effective may be useful. Most of the studies conducted in the area are from high-income countries and are weak in their methodological quality. There is need to conduct more number of rigorous studies, particularly in low and middle-income countries.