Patient age and duration of colonoscopy are predictors for adenoma detection in both proximal and distal colon

Klare, Peter; Ascher, Stefan; Hapfelmeier, Alexander; Wolf, Petra; Beitz, Analena; Schmid, Roland M.; Delius, Stefan von

doi:10.3748/wjg.v21.i2.525

Cited by 9 publications

(8 citation statements)

References 39 publications

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“…Data from a large Korean cohort have shown that especially over and above the 4th decade of life, the ADR reaches 28% as compared to the 2nd decade of life when it is only 14% [7]. Comparable results were published in a large European register [8,9]. Data from the United States [10] endorse European and Asian experiences and stress the importance of raising ADR in patients above 50 years of age.…”

Section: Factors Influencing the Adrsupporting

confidence: 48%

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Floer

Meister²

2016

Digestion

238

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Background: The presence of colorectal adenomas is considered a major risk factor for colorectal cancer development. The implementation of screening colonoscopy programs in the Western world has led to a substantial reduction of colorectal cancer death. Many efforts have been made to reduce the adenoma miss rates by the application of new endoscopic devices and techniques for better adenoma visualization. Summary: This special review gives the readership an overview of current endoscopic innovations that can aid in the increase of the adenoma detection rate (ADR) during colonoscopy. These innovations include the use of devices like EndoCuff® and EndoRings® as well as new technical equipment like third-eye endoscope® and full-spectrum endoscopy (FUSE®). Key Message: Technical improvements and newly developed accessories are able to improve the ADR. However, additional costs and a willingness to invest into potentially expensive equipment might be necessary. Investigator-dependent skills remain the backbone in the ADR detection.

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Section: Factors Influencing the Adrsupporting

confidence: 48%

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Floer

Meister²

2016

Digestion

238

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“…We calculated a sample size by the difference of proximal ADRs in the two groups using PASS software version 11.0 with the procedure of tests for two proportions. On the basis of a previous study, we set the proximal ADR in the EWT group at 13 % [30]. Assuming the proximal ADR in the segmental re-examination group to be 25 %, approximately 175 patients were needed in each group for a statistical power of 80 % or more and a significance level of 0.05.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of segmental re-examination of proximal colon for adenoma detection during colonoscopy: a randomized controlled trial

Guo

Zhang

et al. 2017

Endoscopy

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“…Cabe resaltar que los síntomas que clínicamente sugieren con mayor fuerza la presencia de CCR son sangrado rectal y pérdida de peso (14) , y que en términos generales, la presencia de pólipos colorrectales raramente viene acompañada de síntomas antes de progresar a CCR, excepto por algunas anormalidades ocasionales en la deposición (15) . En nuestra población se encontró mayor incidencia de adenomas en hombres, y el sexo masculino es un factor de riesgo establecido para la presencia de adenomas colorrectales (16) .…”

Section: Discussionunclassified

Incidencia y caracterización de adenomas colorrectales en el área de influencia de una institución especializada

Molina¹,

Ramírez²,

Delfino³

et al. 2022

Rev. colomb. Gastroenterol.

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Objetivo: localización y caracterización endoscópica e histológica de los adenomas colorrectales en una cohorte de pacientes sometidos a colonoscopia en Medellín, Colombia. Materiales y métodos: estudio descriptivo de corte transversal. Se incluyeron pacientes mayores de 18 años sometidos a colonoscopia entre febrero y julio de 2020 en un centro especializado de Medellín, Colombia. Se determinó la incidencia de adenomas, su localización en los diferentes segmentos del colon, sus características endoscópicas e histológicas, así como también los casos de cáncer colorrectal (CCR) y displasia de alto grado. Resultados: se realizaron 992 colonoscopias y se encontraron pólipos colorrectales en 266 pacientes, de los cuales 208 tenían adenomas. En total se resecaron 461 pólipos, de los cuales 336 fueron adenomas (72 %). El tipo histológico con mayor representación fue el tubular (78 %). La localización de adenomas fue del 37 % en el colon derecho, 25 % en el transverso y 38 % en el colon izquierdo. La cantidad de casos de CCR fue de 9 por 1000 pacientes, que incluyen carcinoma avanzado y carcinoma in situ (DAG). Conclusiones: dada la incidencia de adenomas en el colon derecho y transverso, no se recomienda la rectosigmoidoscopia como estudio de tamizaje para CCR. En la población estudiada fueron predominantes los adenomas tubulares, de aspecto sésil y tamaño diminuto. Se recomienda el tamizaje en la población mayor de 40 años y la búsqueda de lesiones precursoras como estrategias para disminuir las tasas de morbimortalidad por CCR.

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Patient age and duration of colonoscopy are predictors for adenoma detection in both proximal and distal colon

Abstract: Increasing age and longer duration of colonoscopy are factors with a strong impact on adenoma detection both in the proximal and distal colon. Since proximal adenomas occurred in absence of distal adenomas, complete colonoscopy should be performed for screening.

Cited by 9 publications

References 39 publications

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Efficacy of segmental re-examination of proximal colon for adenoma detection during colonoscopy: a randomized controlled trial

Incidencia y caracterización de adenomas colorrectales en el área de influencia de una institución especializada

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