Patient blood management in obstetrics – Review

Zdanowicz, Jarmila A.; Surbek, Daniel

doi:10.1016/j.transci.2019.06.017

Cited by 15 publications

(11 citation statements)

References 38 publications

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“…However, as most of the anaemia in pregnancy is due to iron deficiency, therefore adherence to nutrition, and oral iron or parenteral iron is the preferred treatment in such cases before RBC transfusion is considered. 20 A previous study had demonstrated that hemoglobinopathy was among the common causes of anaemia in obstetrics patients, especially in areas where the thalassemia trait is prevalent. 21 Malaysia had recorded about 7,605 cases of thalassemia in 2016; an estimated 150-300 babies were born yearly with severe thalassemia syndromes.…”

Section: Table Iii: Final Regression Model Of Factors Associated With Rbc Transfusion Among Obstetrics Patientsmentioning

confidence: 99%

Factors Contributing to Red Blood Cells Crossmatch and Transfusion among Obstetrics Patients in a Single Tertiary Hospital

Noordin

Ismail²,

Karim

et al. 2022

imjm

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INTRODUCTION: Transfusion of blood and blood components among obstetrics patients is a common practice but they are not without risks. This study aims to determine crossmatch to transfusion ratio (C:T ratio) and to assess the factors that influence red blood cells (RBC) transfusion among obstetrics patients in a single tertiary hospital. MATERIAL AND METHODS: This was a retrospective cohort study of RBC crossmatch requests with data collected from 350 obstetrics patients. The patients were grouped into either received RBC transfusion or did not receive transfusion. Demographics and clinical characteristics were analyzed using descriptive and multivariate analysis. RESULTS: The mean C:T ratio was 3.1. Of 350 patients, 149 (42.6%) patients did receive RBC transfusion. Patients with underlying hemoglobinopathy (75.9%), history of postpartum hemorrhage (63.6%), underwent instrumental assisted delivery (64.3%), and with hemoglobin level of < 70 g/L upon crossmatch requests (90.5%) did receive RBC transfusion. Cesarean section (p=0.011), hemoglobin level < 99 g/L (p<0.001), estimated blood loss > 1000 mL (p<0.001), and symptomatic anemia (p=0.029) were the significant factors associated with RBC transfusion. CONCLUSION: The mean C:T ratio in our study was high. Identifying the factors contributing to RBC transfusion among obstetrics patients are important to reduce unnecessary crossmatch and subsequently improve blood inventory management, and thus further reduce the risks associated with allogeneic transfusion.

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Section: Table Iii: Final Regression Model Of Factors Associated With Rbc Transfusion Among Obstetrics Patientsmentioning

confidence: 99%

Factors Contributing to Red Blood Cells Crossmatch and Transfusion among Obstetrics Patients in a Single Tertiary Hospital

Noordin

Ismail²,

Karim

et al. 2022

imjm

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“…It is also treated by the transplantation of hemopoietic stem cells and by using immunosuppressive regimens. Hemopoietic stem cell transplantation (HSCT) is done after the delivery and it may lead to reduced fertility so the patient is asked before the treatment [25].…”

Section: Treatmentmentioning

confidence: 99%

“…So, in order to maintain hemoglobin concentration in pregnancy intravenous iron (IV), sources are now recommended. Sodium ferric gluconate (Ferrlecit), iron sucrose (Venofer), iron (III)-hydroxide dextran complex (Cosmofer), ferric carboxymaltose (Ferinject), and iron (III) isomaltoside 1000 (Monofer) are now available forms of IV [47]. In order to combat anemia in pregnancy nutritional education or awareness is the main objective [42].…”

Section: Intravenous Iron Source (Iv)mentioning

confidence: 99%

Anemia during Pregnancy and Its Prevalence

Zulkifal¹,

Sarwar²,

Saddique³

et al. 2022

Primary Health Care

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Anemia is a serious health issue throughout the world affecting both sexes of any age group. This nutritional disease is more common among the pregnant women of developing countries, where it is a major cause of maternal death and negative outcome of pregnancy. Among all anemic types, IDA is most prevalent one and is comprises of about 95% of all anemic cases around the world. In many developing countries it is more common in women of low socio-economic background and with no record of antenatal checkup. There is need for further health educational programs to overcome anemia especially for pregnant females.

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“…В течение последнего десятилетия в клиническую практику активно внедряется концепция МКП, объединяю щая врачей многих специальностей2 [8]. Комплексные программы МКП, предлагая эффективные подходы для минимизации периоперационной кровопотери и оптими зированный уход за пациентами, были разработаны и реа лизованы в некоторых странах3.…”

Section: результатыunclassified

Blood management in patients with uterine myoma and anemia in the perioperative period

et al. 2022

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Introduction. In the structure of gynecological diseases, uterine myoma occupies one of the leading places and is accompanied by abnormal uterine bleeding, anemia, hemodynamic and hemostasiological disorders. Purpose. To optimize the management of the perioperative period in patients with uterine myoma and iron deficiency anemia (IDA) using methods of patient blood management (PBM). Materials and methods. The study group consisted of 94 patients with uterine myoma and IDA, who were examined and treated at the Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology. Of these, 74 patients made up the first, prospective group, who received IDA treatment with intravenous administration of ferric carboxymaltose during the perioperative period and during surgical treatment (laparoscopy / laparotomy and myomectomy), they underwent intraoperative autologous blood transfusion (IABT) using the cell salvage with Cell Saver 5+ apparatus. 20 women with myoma uterine and IDA constituted a comparison group (retrospective) who did not receive intravenous iron therapy in the perioperative period and did not undergo IABT. During surgical intervention (laparoscopy / laparotomy and myomectomy) or in the postoperative period, they received transfusion of donor erythrocyte-containing blood components according to indications. Results. All patients underwent surgical treatment in the amount of laparoscopy / laparotomy and myomectomy. During the operation, 74 patients of the main group underwent IABT in an average volume of 467.4 ± 327.8 ml. In the postoperative period, the patients of the main group continued to receive anemia therapy with intravenous administration of ferric carboxymaltose. And blood transfusions were not required in any patient of the main group. In patients of the second group, two (10 %) patients received donor erythrocyte suspension in an average volume of 358.2 ± 85.8 ml. Infectious and inflammatory complications: fever, inflammation of the postoperative suture, parametritis occurred in 6.8 % of women in the main group; in the comparison group – in 15 % of patients. Conclusions. Introduction into clinical practice of modern methods of blood management in patients with uterine myoma and IDA: the Infusion of intravenous high-dose ferric preparationsin the perioperative period, the use of Cell Saver devices for intra-operative autologous blood transfusion, helps to reduce the time of therapy, minimize transfusions of donor erythrocytes, reducing the frequency of infectious and inflammatory complications.

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Patient blood management in obstetrics – Review

Cited by 15 publications

References 38 publications

Factors Contributing to Red Blood Cells Crossmatch and Transfusion among Obstetrics Patients in a Single Tertiary Hospital

Factors Contributing to Red Blood Cells Crossmatch and Transfusion among Obstetrics Patients in a Single Tertiary Hospital

Anemia during Pregnancy and Its Prevalence

Blood management in patients with uterine myoma and anemia in the perioperative period

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