Patient Characteristics Impacting Health State Index Scores, Measured by the EQ-5D of Females with Stress Urinary Incontinence Symptoms

Tincello, Douglas G.; Sculpher, Mark; Tunn, Ralf; Quail, Deborah; Vaart, Huub van der; Falconer, Christian; Manning, Martina; Timlin, L.

doi:10.1111/j.1524-4733.2009.00599.x

Cited by 22 publications

(28 citation statements)

References 20 publications

(24 reference statements)

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“…In this study, type of UI did not predict QoL although it has been suggested that there is a relationship between the type of UI and QoL (Dugan et al, 1998;Senra and Pereira, 2014;Tincello et al, 2010;Yu et al, 2003). In fact, the level of severity of the UI seems to impact more the patient's QoL than the type of UI, as Barentsen et al (2012) have found.…”

Section: Discussioncontrasting

confidence: 56%

Quality of life of women with urinary incontinence in rehabilitation treatment

et al. 2016

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This article analyzed how sexual satisfaction, suffering, severity and impact of urinary incontinence, and psychological morbidity affected women's quality of life and whether suffering mediated the relationship between psychological morbidity and quality of life. The study included 80 women diagnosed with urinary incontinence receiving rehabilitation treatment. Regression analysis showed that sexual satisfaction, suffering, and urinary incontinence severity and impact predicted quality of life and that suffering mediated the relationship between psychological morbidity and quality of life. The findings suggest that interventions should be tailored according to the suffering reported by women and the impact of the urinary incontinence on the couple's sexual relationship.

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Section: Discussioncontrasting

confidence: 56%

Quality of life of women with urinary incontinence in rehabilitation treatment

et al. 2016

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“…Two studies defined groups by the frequency of incontinence episodes [7,19]. In one study, three groups were defined and the mean EQ-5D consistently reflected differences between groups and the differences were statistically significant [19].…”

Section: Resultsmentioning

confidence: 99%

“…In one study, three groups were defined and the mean EQ-5D consistently reflected differences between groups and the differences were statistically significant [19]. In the second study, five groups were defined [7].…”

Section: Resultsmentioning

confidence: 99%

A review of the psychometric performance of the EQ-5D in people with urinary incontinence

Davis

Wailoo

2013

Health and Quality of Life Outcomes

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Urinary incontinence can cause embarrassment and can impact on daily activities and quality of life. Generic health related quality of life instruments, such as the EQ-5D, are designed to be applicable across a variety of disease areas. However, it is sometimes claimed that they are not applicable to a certain disease area because they are missing a domain which directly captures the impact of that particular disease. For example, none of the domains of the EQ-5D relate directly to incontinence, although the impact of incontinence on quality of life may be expected to be picked up indirectly through changes in domains such as usual activities or anxiety/depression. The objective of this review was to examine the appropriateness of the EQ-5D in people with urinary incontinence by reviewing published evidence relating to the psychometric performance of the EQ-5D. A systematic search was conducted to identify studies reporting data that permitted assessment of the construct validity, responsiveness or reliability of the EQ-5D in people with urinary incontinence. Included papers were those that reported EQ-5D alongside other measures of health related quality of life or clinical measures in patients with urinary incontinence or in a broader population where results were reported for a subgroup of patients with urinary incontinence. Data were extracted and a narrative synthesis was undertaken. Seventeen papers were included in the review. In most of the tests performed, EQ-5D was consistent with clinical or disease specific outcome measures. The EQ-5D demonstrated validity in the majority of ‘known group’ comparisons, although statistical significance was not always reported. Correlations between the EQ-5D and disease specific outcomes were statistically significant and in the expected direction for most but not all of the disease specific instruments and clinical measures. For responsiveness, there was general agreement between changes in EQ-5D and changes in clinical or disease specific measures. Evidence on reliability was limited to one study. The EQ-5D was generally found to perform well on tests of construct validity, responsiveness and reliability, in people with urinary incontinence although no definitive conclusion can be made on its appropriateness based on these measures alone.

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“…Because this is a secondary analysis, our data were limited to that originally collected for the primary study. Therefore, the results of our regression analyses are less stable than they would otherwise be with a larger sample size and we were unable to control for confounding factors, such as socioeconomic status and depression, that could impact the prevalence of SUI [20,21]. Some urodynamic parameters, such as leak point pressure, may demonstrate greater variation based on user technique, and therefore may be subject to a larger margin of error.…”

Section: Discussionmentioning

confidence: 97%

Obesity and stress urinary incontinence in women: compromised continence mechanism or excess bladder pressure during cough?

et al. 2017

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Introduction and Hypothesis To compare hypotheses regarding why obesity is associated with stress urinary incontinence (SUI): 1) obesity increases demands on the continence system (e.g. higher cough pressure) vs 2) obesity compromises urethral function and urethrovaginal support. Methods A secondary analysis was performed using data from a case-control study of SUI in women. Measurements of urethrovaginal support (POP-Q point Aa, urethral axis), urethral function (maximal urethral closure pressure (MUCP)), and measures of continence system demands (intravesical pressures at rest and during maximal cough) were analyzed. Cases and controls were divided into three body mass index (BMI) groups: normal (18.5–24.9 kg/m2); overweight (25.0–29.9 kg/m2); and obese (≤30 kg/m2). Logistic regression models where created to investigate variables related to SUI for each BMI group. Structural Equation Modeling was used to test the direct and indirect relationships between BMI, SUI, maximal cough pressure, MUCP, and POP-Q point Aa. Results 108 continent controls and 103 stress-incontinent women were included. MUCP was the factor most strongly associated with SUI for all BMI groups. Maximal cough pressure was significantly associated with SUI for obese women (OR 3.191 (1.326, 7.683), p<.01), but not for normal or overweight women. Path model analyses showed a significant relationship between BMI and SUI through maximal cough pressure (indirect effect, p=.038), but not through MUCP (indirect effect, p=.243) or POP-Q point Aa (indirect effect, p=.410). Conclusions Our results support the first hypothesis: obesity is associated with SUI because of increased intravesical pressure, which therefore increases demand on the continence mechanism.

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Patient Characteristics Impacting Health State Index Scores, Measured by the EQ-5D of Females with Stress Urinary Incontinence Symptoms

Abstract: This article describes the characteristics of patients at the SUIT enrollment visit, and demonstrates that the number of incontinence episodes has a significant impact on the EQ-5D index score.

Cited by 22 publications

References 20 publications

Quality of life of women with urinary incontinence in rehabilitation treatment

Quality of life of women with urinary incontinence in rehabilitation treatment

A review of the psychometric performance of the EQ-5D in people with urinary incontinence

Obesity and stress urinary incontinence in women: compromised continence mechanism or excess bladder pressure during cough?

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