Patient characteristics support unfavorable psychiatric outcome after treatment of unruptured intracranial aneurysms

Abstract

The current study demonstrates an increased rate of positive pre-interventional psychiatric histories in the iA collective. Although those patients represent only a small subgroup, they still may play an important role concerning the overall outcome after iA treatment. Early detection and psychological support in this subgroup might help to improve the overall outcome. Further studies are needed to evaluate the influence of this new aspect on the multifactorial etiology of unfavorable psychiatric outcome after treatment of iA.

Personality and anxiety are related to health-related quality of life in unruptured intracranial aneurysm patients selected for non-intervention: A cross sectional study

“…With respect to personality in patients with UIAs, the study conducted in the Netherlands noted high levels of neuroticism in these patients and a history of previous mental disorders. These results suggest that such precursors could be associated with the low HRQoL levels shown and with the differences found with the comparison group [14][15][16]. However, the study does not establish a relationship between personality traits and the mediation of patient symptomatology, as also found in this study.…”

“…It should be noted that the high prevalence of emotional disturbance in people with UIAs may be associated with personality factors. A previous study reported higher levels of neuroticism and very low levels of openness in patients with UIAs compared to patients with meningioma [14,15]. Secondary analyses of this same study indicated that 37.8% of patients with data collection and analysis, decision to publish, or preparation of the manuscript.…”

“…On this matter, it is important to consider personality factors in the decision process about treatment. Patients with higher levels of neuroticism and low levels of extraversion could have more anxiety about rupture, and those patients could benefit from nonconservative treatment for the aneurysm or be referred to a psychotherapy process [14] oriented to diminishing anxiety levels, which leads to a better HRQoL.…”

Hippocampus subfield volumetry after microsurgical or endovascular treatment of intracranial aneurysms—an explorative study

“…Endovascular coiling and surgical clipping both bear similar risk ratios regarding death, bleeding, cerebral ischemia, and functional independence at daily activities for unruptured intracranial aneurysms [4]. However, differences in cognitive outcome measures for patients after clipping compared to endovascular treatment were described [3,5,21]. Especially patients with incidental aneurysms bear a relatively high burden of pre-interventional psychiatric symptoms [5].…”

“…Both clipping and coiling are widely accepted therapeutic approaches and obviously bear different procedural risks. However, some studies have indicated that patients undergoing surgery are more likely to suffer from impaired cognition and from neuropsychiatric symptoms such as anxiety and depression [5]. A recent study identified postoperative delayed paradoxical depression following surgical repair of unruptured intracranial aneurysms in around 10% of patients, which may be comparable to mild posttraumatic stress disorder and resulted in a reduced rate of patients fully returning to their activities of daily life [6].…”