The purpose of this study was to quantify radiation dose parameters of dual-source CT coronary angiography. Eighty patients underwent contrast-enhanced, retrospectively ECG-gated dual-source CT coronary angiography with heart rate-adapted ECG pulsing using two algorithms: In 40 patients, the tube current was reduced to 20% (A min1 ) of the normal tube current (A max ) outside the pulsing window; in 40 patients tube current was reduced to 4% (A min2 ) of A max . Mean CTDI vol in the A min1 group was 45.1±3.6 mGy; the mean CTDI vol in the A min2 group was 39.1± 3.2 mGy, with CTDI vol in the A min2 group being significantly reduced when compared to the A min1 group (P< 0.001). A significant negative correlation was found between CTDI vol and heart rate in group A min1 (r=−0.82, P< 0.001), whereas no correlation was found between CTDI vol and heart rate in group A min2 (r=−0.066). Using the conversion coefficient for the chest, dual-source CT coronary angiography resulted in an estimated mean effective dose of 8.8 mSv in the A min1 group and 7.8 mSv in the A min2 . Radiation exposure of dual-source CT coronary angiography using an ECG-pulsing protocol reducing the tube current to 20% significantly decreases with increasing heart rates, despite using wider pulsing windows at higher heart rates. When using a protocol with reduced tube current of 4%, the radiation dose is significantly lower, irrespective of the heart rate.