Evidence of the unacceptably high incidence of patient harm associated with health care has resulted in patient safety becoming a major reform agenda. Despite significant investment by governments on strategies to reduce patient harm, confusion still exists on how to measure patient safety.While the goal of patient safety is harm prevention, most of the measurement focus has been on counting incident reports. The (ab)use of reported incident data to measure both technical safety performance (injury rates) and evaluate the effectiveness of safety improvement initiatives continues to confuse and mislead consumers, funders and providers of health care. This paper proposes a simple measurement framework for patient safety which balances the elements of: learning, action, performance, patient experience, and staff attitudes and behaviour. Application of this framework to current priority areas should be used as a basis for patient safety improvement at clinical unit, hospital, state and national levels.OVER THE PAST fifteen years, patient safety has become the focus of significant national and international health reform activity. Despite this, the measurement of patient safety has remained a challenge, particularly at jurisdictional level. This paper seeks to address this issue by proposing a simple patient safety measurement framework involving five measurement domains. All have limited scope, each being best for a specific purpose, but used together can assist an organisation in measuring and improving patient safety.Multiple patient safety measures have been proposed and combined; however, very few assess patient safety performance (true rate of patient harm). It has recently been suggested that "while most hospitals measure some aspect of patient safety, there may not be comprehensive measurement in up to 44% of hospitals", 1 (p. 39) yet these authors did not define or justify a set of measures that would constitute comprehensive measurement for safety. The practical framework outlined in this paper, while pragmatic in its scope, represents a comprehensive view of patient safety measurement. What is known about the topic? It is hard to measure safety performance, that is, the true adverse event or injury rate. Incident reports are often incorrectly used for this purpose. Measures of harm alone are not sufficient to help us determine how to improve safety (ie, for harm prevention). What does this paper add? This paper introduces a comprehensive measurement framework for patient safety. Measures are suggested for the complementary elements of: safety learning, safety performance, patient experience, and staff attitudes and behaviour. Use of measures for all these elements tells us why incidents occur, whether corrective action is being undertaken, the quanta of harm, whether patients feel safe and about the organisational safety culture. What are the implications for practitioners? Application of this measurement framework produces a comprehensive assessment of patient safety. Use of the framework will ens...