ag ing, The Af fil i ated Hos pi tal (group) of Putian Uni ver sity, Fujian, China 3 De part ment of Radiologic On col ogy, Chung Shan Med i cal Uni ver sity Hos pi tal, Chung Shan Med i cal Uni ver sity, Tai wan, Re pub lic of China 4 School of Med i cine, Chung Shan Med i cal Uni ver sity, Tai wan, Re pub lic of China, 5 De part ment of Nu clear Med i cine, Landseed Hos pi tal, Ping-jen, Tao-Yuan City, Tai wan, Re pub lic of China 6 De part ment of Med i cal Im ag ing and Ra dio log i cal Sci ences, Chung Shan Med i cal Uni ver sity, Tai wan, Re pub lic of China Sci en tific pa per