Patient management and clinical outcomes in non-traumatic small bowel perforations

Abstract

ÖZET Amaç: Bu çalışmanın amacı, travmatik olmayan ince barsak perforasyonu nedeniyle ameliyat edilen hasta yönetimimizi ve sonuçlarını sunmaktır.Yöntemler: Kliniğimizde 2005 ve 2013 arasında travmatik olmayan ince bağırsak perforasyonu nedeniyle ameliyat edilen 30 hastanın kayıtları incelendi. Hastalara ait yaş, cinsiyet, şikayetler, belirtilerin süresi, eşlik eden hastalık(lar), perforasyon yeri, hastanede kalış süresi, etyoloji, cerrahi tedavi, morbidite ve mortalite verileri kaydedildi. Hastalar yaşayanlar ve ölenler olmak üzere iki gruba ayrıldı ve grupların çeşitli özellikleri karşılaştırıldı. Bulgular:Hastaların yaş ortalaması 51,3±19,9 yıl idi. Periton irritasyonu bulguları 22 (% 73,3) hastada vardı. Eksplorasyonda 14 (% 46,6) hastada yaygın pürülan peritonit gözlenirken, diğerlerinde lokalize peritonit mevcuttu. Primer sütürasyon sadece 3(%10) hastaya uygulanırken, barsak rezeksiyonu 27 (%90) hastaya uygulandı. Saptırıcı ileostomi 18 (%60) hastaya uygulandı. Mortalite 9 (%30) hastada gözlendi. Semptom süresi ve çoklu perforasyon varlığı mortalite gelişen hastalarda anlamlı derecede yüksek bulundu.Sonuç: Tanıda gecikme ve çoklu perforasyon varlığı mortalitenin en önemli nedenleridir. Tanıda gecikmeyi önlemek için her türlü çaba harcanmalıdır; ancak, eğer tanı gecikmişse, özellikle çoklu perforasyonu olan hastalarda bağırsak rezeksiyonu ve/veya ileostomi gibi geniş cerrahi prosedürlerden kaçınılmamalıdır.Anahtar kelimeler: Travmatik olmayan, ince bağırsak delinmesi, tanı, yönetim ABSTRACT Objective: The aim of this study was to report our management and outcomes of patients who underwent surgery with the diagnosis of non-traumatic small bowel perforation. Methods:The records of 30 patients who underwent surgery for non-traumatic small bowel perforation between 2005 and 2013 were examined. Age, gender, complaints, duration of symptoms, comorbid disease(s), perforation location, length of stay in hospital, etiology, surgical treatment, morbidity, and mortality data were recorded. Patients were divided into two groups, survivors and nonsurvivors, and their features were compared. Results:The mean age of the patients was 51.3±19.9 years. Signs of peritoneal irritation were present in 22(73.3%) patients. In surgical exploration, generalized purulent peritonitis was observed in 14(46.6%) patients, while localized peritonitis was observed in the others. Bowel resection was performed in 27(90%) patients, while primary suture was performed in only 3(10%) patients. A diverting ileostomy was performed in 18(60%) patients. Mortality was observed in 9 (30%) patients. Duration of the symptoms and multiple perforations were significantly higher in non-survivors. Conclusion:A delay in diagnosis and presence of multiple perforations are the most important causes of mortality. Every effort should be made to avoid delay in diagnosis; however, once the diagnosis is delayed, especially in patients with multiple perforations, extensive surgery such as bowel resection and ileostomy should not be avoided. J Clin Exp Invest 2015; 6...

Prevalence, Anatomic-pathologic Findings, and Associated Factors of Nontraumatic Ileal Perforations Among Patients with Gut Perforation: A Multicenter Cross-sectional Study

“…A similar study Türkoğlu et al, (25) in Turkey reported that approximately 70% of participants presented with a single perforation.…”

An additional cause to be introduced in the inventory of non-traumatic perforations of the small intestine: gallstone migration.

“…[1]. Although infectious causes, especially typhoid and tuberculosis are forefront in developing countries, Crohn's disease and malignancies are more common in developed countries [3]. Rare causes of perforation include lymphoma, malignant small intestin tumor, Crohn's disease and internal hernia, which account to only 5.4% according to the retrospective study of a Turkish team aiming to track down all causes of small bowel perforation [4].…”