“…Various approaches to image-guided radiation therapy (IGRT) have been proposed. Amongst these are implanted radio opaque markers (Balter et al 1995, Litzenberg et al 2002, Sandler et al 1993, implanted magnetic markers (Lennernas 1997, Lennernas et al 1999, Lennernas and Nilsson 1995, ultrasound systems (Bouchet et al 2001, Lattanzi et al 1999, Morr et al 2002, Tome et al 2002, CT/LINAC (Cheng et al 2003, Court et al 2003, MVCT (Mackie et al 1993, Swindell 1983, MV cone-beam CT (Ford et al 2002, Midgley et al 1998, Mosleh-Shirazi et al 1998, Pouliot et al 2005, Seppi et al 2003 and kV cone-beam CT (Berbeco et al 2004, Jaffray et al 1999, 2002, Jaffray and Siewerdsen 2000. Each system has advantages and disadvantages and no one method has emerged as clearly superior.…”