Patient Preference and Willingness-to-Pay for Humalog Mix25 Relative to Humulin 30/70: A Multicountry Application of a Discrete Choice Experiment

Objectives: To systematically review the existing literature on the value associated with convenience in health care delivery, independent of health outcomes, and to try to estimate the likely magnitude of any value found. Methods: A systematic search was conducted for previously published studies that reported preferences for convenience-related aspects of health care delivery in a manner that was consistent with either cost-utility analysis or cost-benefit analysis. Data were analyzed in terms of the methodologies used, the aspects of convenience considered, and the values reported. Results: Literature searches generated 4715 records. Following a review of abstracts or full-text articles, 27 were selected for inclusion. Twentysix studies reported some evidence of convenience-related process utility, in the form of either a positive utility or a positive willingness to pay. The aspects of convenience valued most often were mode of administration (n ¼ 11) and location of treatment (n ¼ 6). The most common valuation methodology was a discrete-choice experiment containing a cost component (n ¼ 15). Conclusions: A preference for convenience-related process utility exists, independent of health outcomes. Given the diverse methodologies used to calculate it, and the range of aspects being valued, however, it is difficult to assess how large such a preference might be, or how it may be effectively incorporated into an economic evaluation. Increased consistency in reporting these preferences is required to assess these issues more accurately.

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“…Two studies had multinational perspectives [38,39]. Study characteristics are expanded upon in Table 1.…”

Section: Key Characteristics Of Studiesmentioning

confidence: 99%

Does Convenience Matter in Health Care Delivery? A Systematic Review of Convenience-Based Aspects of Process Utility

Higgins

Barnett

Meads³

et al. 2014

Value in Health

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“…In health economics, the number of DCE studies has sharply increased during the past decade [8][9][10][11][12]. More specifically, many DCE applications have aimed to evaluate the health and non-health dimensions of medical treatments, for example: miscarriage management [13]; varicella vaccination [14]; insulin mixtures [15]; alcoholism medication [16]; colorectal cancer screening [17]; weight loss programmes [18]; knee injuries detection [19]; and lower urinary tract symptoms [20]. In Table 1, we provide a nonexhaustive list of empirical papers using DCE to value medical interventions along with the dimensions that were assessed.…”

Section: Related Workmentioning

confidence: 99%

Assessing preferences for improved smoking cessation medications: a discrete choice experiment

Marti

2011

Eur J Health Econ

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Background The use of smoking cessation medications can considerably enhance the long-term abstinence rate at a reasonable cost, but only a small proportion of quitters seek medical assistance. The objective of this study was to evaluate the factors that influence the decision to use such treatments and the willingness-to-pay of smokers for improved cessation drugs. Method A discrete choice experiment was conducted amongst smokers in the French-speaking part of Switzerland. Choice sets consisted of two hypothetical medications described via five attributes (price, efficacy, possibility of minor side effects, attenuation of weight gain and availability) and an opt-out option. Various discrete choice models were estimated to analyse both the factors that influence treatment choice and those that influence the overall propensity to use a smoking cessation medication. Results Our results indicate that smokers are willing to pay for higher efficacy, less-frequent side effects and prevention of weight gain. Whether the drug is available overthe-counter or on medical prescription is of secondary importance. In addition, we show that there are several individual-specific factors influencing the decision to use such medications, including education level. Results also indicate substantial preference heterogeneity. Conclusion This study shows that there is a potential demand for improved cessation medications. Broader usage could be reached through lower out-of-pocket price and greater efficacy. Secondary aspects such as side effects and weight gain should also be taken into consideration.

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“…A growing body of research has assessed patients' preferences for one form of insulin therapy versus another [1,2] and satisfaction with insulin delivery [3,4]. Few studies have investigated preference and satisfaction among patients taking only oral antihyperglycemic agents (OHA) [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Reliability and validity of an instrument for assessing patients’ perceptions about medications for diabetes: the PAM-D

et al. 2009

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Patient Preference and Willingness-to-Pay for Humalog Mix25 Relative to Humulin 30/70: A Multicountry Application of a Discrete Choice Experiment

Abstract: Patients in all countries showed a preference and WTP for Humalog Mix25 over Humulin 30/70. The main drivers of patient WTP may be of interest to pharmaceutical prescribers, manufacturers, and reimbursement agencies.

Cited by 54 publications

References 19 publications

Does Convenience Matter in Health Care Delivery? A Systematic Review of Convenience-Based Aspects of Process Utility

Does Convenience Matter in Health Care Delivery? A Systematic Review of Convenience-Based Aspects of Process Utility

Assessing preferences for improved smoking cessation medications: a discrete choice experiment

Reliability and validity of an instrument for assessing patients’ perceptions about medications for diabetes: the PAM-D

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