Objective The in¯uence of the type of abdominal incision on post-operative pain and pulmonary function was investigated in patients operated upon for a rightsided cancer of the large bowel.Patients and methods Fifty-three patients scheduled for a right hemicolectomy due to a right-sided colon cancer were randomized to a median vertical (M) or a transverse incision (T). Forty patients, 23 with a M and 17 with a T incision, completed the study and could be evaluated. Pain at rest and after physical activity was assessed with a visual analogue scale, and was also measured as re¯ected in the need for analgesics. Respiratory function was assessed with pre-and post-operative spirometry.Results Pain after activity was signi®cantly less in patients with a T incision. This group also needed less analgesia. Vital capacity (VC) and forced expiratory volume in 1 s (FEV 1.0) were profoundly reduced after surgery in both groups of patients, but improvement of respiratory function was faster in patients with a transverse incision. No problem with access to the operative ®eld was noted.Conclusion We conclude that a transverse incision is preferable to a midline incision and should be used in right hemicolectomy. This abdominal incision reduces effort-induced pain and interferes less with post-operative pulmonary function, and may reduce the risk of pulmonary complications.Keywords Colon cancer, transverse incision, midline incision, post-operative pain, pulmonary function P. G. Lindgren et al.Midline or transverse abdominal incision for right-sided colon cancer