Patient-Reported Measures of Physical Function in Knee Osteoarthritis

White, Daniel K.; Master, Hiral

doi:10.1016/j.rdc.2016.01.005

Cited by 64 publications

(45 citation statements)

References 45 publications

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“…This study represents an important step forward in our understanding of the use of PROs in adult reconstruction patients. With this work, along with other similar studies in lower extremity populations, it is plausible that we may find a way of incorporating advanced PRO tools, using CAT, that are also more generalized and still quite sensitive and responsive to patients undergoing very specific interventions. Thus, the use of a different survey for every different joint or surgical intervention in the human body may become obsolete as we begin to move forward with more globalized, low burden, but highly responsive questionnaires that could be used across multiple medical subspecialties and patient types.…”

Section: Discussionmentioning

confidence: 73%

Evaluating instrument responsiveness in joint function: The HOOS JR, the KOOS JR, and the PROMIS PF CAT

Hung

Saltzman

Greene

et al. 2017

Journal Orthopaedic Research

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Section: Discussionmentioning

confidence: 73%

Evaluating instrument responsiveness in joint function: The HOOS JR, the KOOS JR, and the PROMIS PF CAT

Hung

Saltzman

Greene

et al. 2017

Journal Orthopaedic Research

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“…The patients filled the WOMAC questionnaire by selecting one of the possible answers (by marking it with "X") where 0 indicates none, 1 mild, 2 moderate, 3 serious and 4 hard. Each subscale is added separately, where higher scores indicate poorer health and physical functioning [11].…”

Section: Methodsmentioning

confidence: 99%

The impact of pain on functionality and health related quality of life in patients with knee osteoarthritis

et al. 2019

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Introduction/Objective Pain, stiffness and limited mobility are the main factors that lead to difficulties in performing daily activities and are also responsible for the decline in the quality of life in people with knee osteoarthritis (OA). The aim of this study was to evaluate the functional capacity and health related quality of life (HRQoL) compared to pain in patients with knee OA, as well as to determine the correlation between these three clinical variables. Methods The study involved 931 patients diagnosed with knee OA. In all patients, pain was evaluated by a short form of the McGill pain questionnaire (SF-MPQ), functional status was assessed using the Western Ontario and McMaster Universities Arthritis Index (WOMAC), while life quality was evaluated using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Results The average age of patients was 61.21 ± 4.62 years, while 71.3% of them were women. The quality of life in patients with knee OA and all pain parameters contained in the SF-MPQ were highly statistically positively associated (p ≤ 0.01). In addition, the physical functioning was mostly affected by emotional pain (rho =-0.585). A high statistical correlation (p ≤ 0.01) was noted between stiffness and physical functioning from the WOMAC questionnaire and all of the parameters from the SF-MPQ. The physical functioning from the WOMAC questionnaire had the strongest correlation with total pain incorporated into the McGill questionnaire (rho = 0.530). Conclusion Knee pain has a significant impact on functional capacity and HRQoL in patients with knee OA. Therefore, one of the main therapy goals for OA of the knee should be to reduce the pain in the affected knee, which can help to improve the functionality and HRQoL of these patients.

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“…However, as identified in 2 recent systematic reviews, the responsiveness or MIDs of PROMIS instruments are unknown in OA. 25,77 Therefore, a longitudinal examination of how PROMIS instruments perform in OA will fill an important research gap.…”

Section: Introductionmentioning

confidence: 99%

Responsiveness and Minimally Important Differences for 4 Patient-Reported Outcomes Measurement Information System Short Forms: Physical Function, Pain Interference, Depression, and Anxiety in Knee Osteoarthritis

Lee

Driban

Price

et al. 2017

The Journal of Pain

158

150

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Patient-Reported Outcomes Measurement Information System (PROMIS) instruments can provide valid, interpretable measures of health status among adults with osteoarthritis (OA). However, their ability to detect meaningful change over time is unknown. We evaluated the responsiveness and minimally important differences (MID) for four PROMIS Short Forms: Physical Function, Pain Interference, Depression, and Anxiety. We analyzed adults with symptomatic knee OA from our randomized trial comparing Tai Chi and physical therapy. Using baseline and 12-week scores, responsiveness was evaluated according to consensus standards by testing 6 a priori hypotheses of the correlations between PROMIS and legacy change scores. Responsiveness was considered high if ≥5 hypotheses were confirmed, and moderate if 3 or 4 were confirmed. MIDs were evaluated according to prospective change for people achieving previously-established MID on legacy comparators. The lowest and highest MIDs meeting a priori quality criteria formed an MID range for each PROMIS Short Form. Among 165 predominantly female (70%) and white (57%) participants, mean age was 61 years and body mass index was 33kg/m2. PROMIS Physical Function had 5 confirmed hypotheses and Pain Interference, Depression, and Anxiety had 3 or 4. MID ranges were: Depression=3.0–3.1; Anxiety=2.3–3.4; Physical Function=1.9–2.2; and Pain Interference=2.35–2.4. PROMIS Physical Function has high responsiveness, and Depression, Anxiety, and Pain Interference have moderate responsiveness among adults with knee OA. We established the first MIDs for PROMIS in this population, and provided an important standard of reference to better apply or interpret PROMIS in future trials or clinical practice.

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Patient-Reported Measures of Physical Function in Knee Osteoarthritis

Cited by 64 publications

References 45 publications

Evaluating instrument responsiveness in joint function: The HOOS JR, the KOOS JR, and the PROMIS PF CAT

Evaluating instrument responsiveness in joint function: The HOOS JR, the KOOS JR, and the PROMIS PF CAT

The impact of pain on functionality and health related quality of life in patients with knee osteoarthritis

Responsiveness and Minimally Important Differences for 4 Patient-Reported Outcomes Measurement Information System Short Forms: Physical Function, Pain Interference, Depression, and Anxiety in Knee Osteoarthritis

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