Patient-reported Outcome Measures After Hospitalization During the COVID-19 Pandemic, a Survey Among COVID-19 and Non-COVID-19 Patients.

Abstract

Background: Many people recovering from COVID-19 suffer from long-term sequelae. The objective of this study was to assess health-related quality of life (HRQoL) in COVID-19 patients a few months after discharge. Methods: We conducted a retrospective cross-sectional case-control study on COVID-19 and non-COVID-19 pneumonia patients admitted to Shamir Medical Center, Israel (03-07/2020). In the months following discharge, patients were invited to participate in a survey and fill the RAND-36 questionnaire. Patient's characteristics and comorbidities were extracted from electronic charts. Results: Among 66 COVID-19 participants, the median age was 58.5 (IQR 49.8-68.3), 56.1% were female, and more than a third were obese (36.4%). The median length of stay was 7 days (IQR 4-10). Patient-reported outcome measures were reported at a median follow-up of 9-months (IQR 6-9). Pain, general health, vitality, and health change had the lowest scores (67.5, 60, 57.5, and 25 respectively). Matching to patients hospitalized with pneumonia due to other pathogens was performed on 42 of the COVID-19 patients. Non-COVID-19 patients were more frequently current or past smokers (50% vs 11.9%, p<0.01) and suffered more often from chronic lung disease (38.1% vs 9.5%, p=0.01). The score for health change was significantly lower in the COVID-19 group (25 vs 50, p<0.01). Conclusions: Post COVID-19 patients continue to suffer from an assortment of symptoms and perceive a deterioration in their health many months after hospitalization. This emphasizes the importance of prolonged medical follow-up in this population, and the need for additional research to better understand this novel's disease long-term effects.

Ambulante Rehabilitative Versorgung von Patienten mit Long-COVID – eine leitlinienorientierte klinisch-praktische Handlungsempfehlung

“…Nach Entfernung von Duplikaten und Prüfung der Einschlusskriterien verblieben 61 Artikel, die für die folgende Arbeit als Basis dienten ( Abb. 1 ) 2 3 4 5 7 9 10 11 12 13 15 16 17 18 20 22 24 25 28 29 30 31 33 34 37 38 41 42 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 . Sie werden als Grundlage der Empfehlungen in den einzelnen Unterkapiteln des Abschnitts 3 verwendet und dort zitiert.…”

Mental health and chest CT scores mediate the relationship between COVID-19 vaccination status and seroconversion time: A cross-sectional observational study in B.1.617.2 (Delta) infection patients

“…Previous work on the long-term impact of COVID-19 on mental health is extensive (27)(28)(29) and has shown that functional mobility impairment, pulmonary abnormalities, and mental health disorders are the most common postacute sequelae of COVID-19 infection (30). However, these studies were usually meta-analyses and did not consider vaccination status.…”