Patient reported outcomes following breast conserving surgery are improved by minimizing re-excisions and excessive breast tissue removal

γ-Glutamyltranspeptidase and pH based “AND” logic gate fluorescent probe for orthotopic breast tumor imaging

“…1,2 Total mastectomy is still the first line of surgical therapy, but the volume of breast tissue removed negatively affects the psychological and physical fitness of patients. 3,4 To reduce both the removed tissue and the chance of recurrence, accurate intraoperative localization of the tumor and its boundary is required. As reported, intraoperative real-time visualization of cancer cells by a logic gate-based fluorescent probe is a highly pursued strategy to achieve that goal.…”