Patient-reported outcomes in the aging population of adults with congenital heart disease: results from APPROACH-IS

Abstract

The congenital heart disease (CHD) population now comprises an increasing number of older persons in their 6th decade of life and beyond. We cross-sectionally evaluated patient-reported outcomes (PROs) in persons with CHD aged 60 years or older, and contrasted these with PROs of younger patients aged 40–59 years and 18–39 years. Adjusted for demographic and medical characteristics, patients ≥60 years had a lower Physical Component Summary, higher Mental Component Summary, and lower anxiety (Hospital Anxiety and Depression Scale-Anxiety) scores than patients in the two younger categories. For satisfaction with life, older persons had a higher score than patients aged 40–59 years. Registration: ClinicalTrials.gov NCT02150603.

Remission from depression is associated with improved quality of life and preserved exercise capacity in adults with congenital heart disease

“…In this regard, the association of depression and depressive symptoms with low QoL is well established in ACHD ( 23 , 26 , 27 ). Additionally, reduced exercise capacity, age, and anatomical complexity of the underlying heart defect have been established as significant moderators of QoL in ACHD ( 25 , 27 , 28 ).…”