Patient-Reported Quality of Life Before and After Total Knee Arthroplasty: A Multicenter Observational Study

Abstract

Purpose To compare patients’ self-reported health-related quality of life (HRQoL) before and after total knee arthroplasty (TKA) and determine factors contributing to any heterogeneity in HRQoL. Patients and Methods This prospective multicenter observational study included 404 patients with knee osteoarthritis who underwent TKA between April 1, 2019 and December 30, 2019 and whose HRQoL was assessed preoperatively and 7 days and 1, 3, and 6 months postoperatively. Sociodemographic characteristics were assessed using a General Information Questionnaire, disability using the Knee Injury and Osteoarthritis Outcome Score (KOOS-PS), resting pain using the visual analogue scale (Pain-VAS), and HRQoL using the European Quality of Life Five Dimension Five Level (EQ-5D-5L) scale. The growth mixture model was used to identify group heterogeneity in the developmental trajectories of KOOS-PS, Pain-VAS, and EQ5D5L. Logistic regression was used to explore the factors influencing the developmental trajectories of factors affecting the developmental trajectory of HRQoL. Results The mean EQ-5D-5L score improved from 0.69 preoperatively to 0.90 at 6 months postoperatively. Longitudinal heterogeneity in HRQoL was observed in patients during recovery: 1) patients with a small and slow improvement in HRQoL and 2) patients who showed marked and rapid improvement in HRQoL. The main characteristics of the latter group were decreasing VAS pain scores, a monthly family income >2000 CNY (100 CNY equals approximately 14.9 USD), exercising for <30 min daily, and better knee function at baseline. Baseline knee function and change in knee function were significantly associated with the percentage change in HRQoL. Conclusion HRQoL improved considerably after TKA. However, there was heterogeneity in the changes in HRQoL depending on patients’ socioeconomic status, exercise, and baseline knee function. Dynamic tracking of the HRQoL of TKA patients and timely provision of rehabilitation guidance will promote continuous improvement of the HRQoL of TKA patients.

The dynamic impact of Joint Awareness on Quality of Life after Total Knee Arthroplasty: a longitudinal study

“…We also found that QoL advanced over time, consistent with other studies that have found that QoL at 3 months after TKA was better compared to that before TKA and that people resumed the vast majority of their daily activities at 12 months after TKA [ 9 , 26 ]. For a patient to undergo TKA, it must be perceived as high value in improving knee functions and relieving pain, and postoperative high intensity exercise and remote rehabilitation may be helpful in reducing joint stiffness [ 27 , 28 ]. Therefore, the physiological QoL can be improved accordingly during postoperative time.…”

Knee Joint Replacement: A Study Of The Patient Profile In Central India

“…In our study, main indication for total knee replacement here also in about 70% patients. As per literature, over 95 percent of TKAs in the United States are performed for osteoarthritis [9,10,11,12,13,14,15]. There are few conditions like morbid obesity and severe osteoporosis which may hamper successful knee arthroplasty procedure.…”

“…Total knee replacement or Knee arthroplasty has made a revolution in treatment of painful conditions like osteoarthritis or rheumatoid arthritis could now be solved by replacing the damaged joint with an artificial joint which dramatically improves the pain of the patient and the person who could barely walk due to pain starts walking again pain free. [9,10]. Due to economic reasons and the rumors that joint replacements are not safe and effective, many potential candidates for it did not undergo the operation and continued taking painkillers or herbs and applying ayurvedic oils and massaging the joints but the effects of all these are temporary and not up to the mark [2,9,10,11,12].…”

“…[9,10]. Due to economic reasons and the rumors that joint replacements are not safe and effective, many potential candidates for it did not undergo the operation and continued taking painkillers or herbs and applying ayurvedic oils and massaging the joints but the effects of all these are temporary and not up to the mark [2,9,10,11,12]. With the new equipment and the expertise of the surgeons, hardly any complications are seen in arthroplasty operations.…”

“…With the new equipment and the expertise of the surgeons, hardly any complications are seen in arthroplasty operations. Pain is the number one indication for a total knee replacement [1,2,10,12]. The conservative management is initially tried but if it is ineffective, Total Knee Replacement is the only option left.…”