“…The most common adverse effects were temporomandibular joint (TJM) pain (9/10 studies) [2,31,35e38,43e45]; excessive salivation (7/10 studies) [2,24e26,31e33,45]; sensitivity in muscles or teeth (7/10 studies) [2,35,38,39,43e45]; and dry mouth or throat (5/10 studies) [2,20,35,38,44]. Notably, five studies reported progressive diminution of these side effects during treatment [2,20,31,36,43].…”