“…The application of the material in the oral cavity, i.e., in direct contact with tissues, places special demands on this group of biomaterials regarding their physicochemical and biological properties, i.e., biocompatibility, local and general harmlessness to the organism [ 18 , 21 , 22 ], resistance to the effects of physicochemical factors in the oral cavity [ 21 ] and biophysical indifference [ 18 , 19 ]. In addition, the accuracy in mimicking natural tooth shapes [ 19 ], stability of mechanical properties [ 19 , 22 ], ease processing [ 21 , 23 ], appropriate aesthetics [ 19 , 24 ], and finally a moderate price [ 19 , 23 ] are further requirements that need to be met. The first phenomenon that occurs after the introduction of the biomaterial into the oral cavity is the formation of a biofilm on its surface [ 25 , 26 , 27 ].…”