Patient satisfaction with antihypertensive therapy

Abstract

The objective of the study was to assess factors associated with treatment satisfaction among patients receiving antihypertensive therapy. A weighted crosssectional online survey was conducted with hypertensive patients participating in a chronic disease panel in the US. Patients on monotherapy with medications from the following classes were identified: ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), beta blockers (BBs), calcium channel blockers (CCBs), and diuretics. The control group included patients without treatment. Pairwise comparisons between groups were conducted for factors that may affect patients' satisfaction. The study population had a mean age of 54.7714.2 years and was 56.7% female. Participants with blood pressure (BP) controlled to JNC 7 guidelines were more satisfied with their medication than those with uncontrolled BP (90.3 vs 71.5%, Po0.05). Patients who had not experienced adverse events had higher satisfaction than patients experiencing adverse events (90.9 vs 75.8%, Po0.05). The most frequently self-reported adverse events were frequent urination, sexual dysfunction, and fatigue ranging from 7.0 to 9.6% across classes. The adverse event rates differed by class and were lowest among the ARBs. Patients on ARBs were the most likely to have switched from a previous antihypertensive class as compared to other classes (57.1% ARBs vs 49.8% ACEIs, 38.7% diuretics, 36.3% CCBs, and 31.7% BBs). Physician recommendation was the most common reason for switching. In conclusion, the ability to effectively treat hypertension depends upon a patient's satisfaction with antihypertensive therapy, which may be improved by achieving BP control and minimizing the occurrence of adverse events.

Questionnaire Survey From the Viewpoint of Concordance in Patient and Physician Satisfaction Concerning Hypertensive Treatment in Elderly Patients ― Patients Voice Study ―

“…19, 20 Chen et al reported that the incidence of AEs ranged from 7.0% to 9.6% in patients receiving antihypertensive drugs, and that patients who had not experienced AEs had higher satisfaction. 21 In the present study, there were relatively low incidence rates for AEs (4.7%) and ADRs (2.4%). Thus, there is a possibility that the efficacy, adherence, study activities, and low incidence of AEs cooperatively contributed to improving the BP control and the General health scores.…”

Stress Management Versus Lifestyle Modification on Systolic Hypertension and Medication Elimination: A Randomized Trial

“…8,9 Many antihypertensive treatments cause sideeffects such as dizziness, headache, fatigue, chest discomfort/cough, and sexual dysfunction, prompting some patients to discontinue therapy. 10,11 Since 40% of the elderly in the United States take five or more medications daily, they are also at greater risk for side-effects and drug-drug interactions. 12 Safe and effective nonpharmacologic approaches to treat SH are of interest and public health importance.…”

Association Between Antihypertensive Medication Use and Non-cardiovascular Outcomes in Older Men

“…Treatment of hypertension with multiple medications to achieve cardiovascular benefits must therefore be balanced against potential harms. Previous studies have shown that antihypertensive medications are associated with potential drug effects apart from their intended cardiovascular outcomes, including changes in the domains of muscle function, [7][8][9] energy level and fatigue, 10,11 and cognition. 12 Although data from the Systolic Hypertension in the Elderly Program Trial 13 did not provide evidence of an impact of antihypertensive drug use on several measures of cognition, physical function, and mood, 14 few data are available regarding whether older adults who routinely take these drugs in usual practice are at increased risk for adverse noncardiovascular outcomes.…”