Patient satisfaction with treatment decisions for clinically localized prostate carcinoma. Results from the Prostate Cancer Outcomes Study

Hoffman, Richard M.; Hunt, William C.; Gilliland, Frank D.; Stephenson, Robert A.; Potosky, Arnold L.

doi:10.1002/cncr.11233

Cited by 146 publications

(136 citation statements)

References 26 publications

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“…18 In line with our results, Hoffman and colleagues showed that 75% of those who developed daily urinary incontinence still reported that the poor function was at most only a small problem. 19 Consequently, the recovery from urinary bother was observed early at 6 months and in the remaining postoperative periods, showing that postoperative incontinence was, if any, minimal in the majority of the patients and their problems were not so severe.…”

Section: Discussionmentioning

confidence: 88%

Quality of life after radical prostatectomy in Japanese men: A 5‐Year follow up study

Namiki¹,

Ishidoya²,

Ito³

et al. 2008

Int J of Urology

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Objectives: To measure health-related quality of life (HRQOL) after radical prostatectomy (RP) in Japanese men with localized prostate cancer. Methods: A total of 154 patients who underwent RP were included in this 5-year longitudinal survey. The Short Form 36-Item Health Survey, the University of California, Los Angeles, Prostate Cancer Index and the International Prostate Symptom Score questionnaires were administered at diagnosis and nine times afterwards. Results: Patients undergoing RP showed problems in some physical domains of general HRQOL, but these problems diminished over time. Mental health and social functions significantly improved during the follow-up period. The urinary function substantially declined at 3 months and continued to recover gradually but never returned to baseline. Most patients (95%) recovered to their baseline urinary bother score within 60 months. The overall mean total International Prostate Symptom Score progressively improved with time. On the other hand , at 60 months after RP, only 34% of subjects had fully returned to baseline sexual function. By 5 years postoperatively, 78% of the men had reached baseline sexual bother and the mean recovery time was 8.6 months. Adverse effects of RP on sexual function and bother were mitigated by bilateral nervesparing procedures up to 5 years after the operation. Conclusions: Despite reported problems with sexuality and urinary continence, general HRQOL was mostly unaffected by RP after 6 months in our survey with functional outcomes remaining relatively stable in the majority of patients.Key words: longitudinal study, prostate cancer, quality of life, radical prostatectomy. IntroductionCurrently, the most common therapeutic options for localized prostate cancer are radical prostatectomy (RP), external radiation, and interstitial brachytherapy. RP is considered an especially safe and effective treatment for localized prostate cancer and has gained popularity among Japanese urologists over the last decade.1 As prostate cancer is increasingly diagnosed at early stages and therefore with more favorable survival outcomes, the basis on which patients select primary therapy has shifted toward considerations of health-related quality of life (HRQOL). 2,3Accordingly, HRQOL assessment has become an important form of outcome-based research that may weigh heavily on the justification of health care expenditures and the treatment selection by patients.Several assessments of HRQOL after prostate cancer treatment have been limited to studies of non-Hispanic whites, African-Americans, and Hispanics in the USA.4,5 Previously, we detailed HRQOL recovery in Japanese men with localized prostate cancer followed for 2 years after RP. 6 In the current analysis we assessed temporal changes in HRQOL up to 5 years following RP using validated questionnaires. To our knowledge the current study is the longest-term prospective study to assess the impact of RP on general and disease-specific outcomes following RP in Japanese men with clinically localized prostate can...

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Section: Discussionmentioning

confidence: 88%

Quality of life after radical prostatectomy in Japanese men: A 5‐Year follow up study

Namiki¹,

Ishidoya²,

Ito³

et al. 2008

Int J of Urology

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“…There did not seem to be any statistical differences in terms of ED in between the types of ADT therapy. In a later study 64 by the same group, 86% of men undergoing ADT subsequently experienced ED, compared to 58% of radical prostatectomy patients, 43% of radiotherapy patients and 33% patients undergoing watchful waiting (P,0.0001). In another study by Potosky et al, 65 the erectile function outcomes of a cohort of 88 ADT patients were compared to a matched group of 223 prostate cancer patients receiving no treatment.…”

Section: Edmentioning

confidence: 88%

Impact of androgen deprivation therapy on sexual function

Mazzola

Mulhall²

2012

Asian J Androl

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Many patients with prostate cancer for whom androgen deprivation therapy (ADT) is indicated are young and desire to remain sexually active. In such patients, the side effects of androgen therapy on sexual function can be a source of serious reduction in overall quality of life. Providing the appropriate treatment options in this patient population is therefore essential. Nevertheless, treating such patients is challenging and an understanding of the underlying mechanisms of sexual physiology and pathophysiology is crucial to optimal patient care. In this paper, we reviewed what was known regarding the effects of ADT on sexual function in animal models and we also provided a detailed review on the effects of ADT on sexual health in humans and its treatment.

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“…Örneğin, Hoffman ve ark.nın yaptıkları çalışmada, İspan-yol kökenli hastaların diğer hastalara göre memnuniyetlerinin daha düşük olduğu belirtilmekte ve hastalığın algılanması ile tedavi memnuniyetinin etnik kökene bağlı olarak değişkenlik gösterebil-diği vurgulanmaktadır. 12 Bu çalışmanın sonuçları ülkemizdeki etnik ve/veya sosyokültürel farklılık-lara göre tedavi algısını değerlendirmek için yeterli düzeyde olmamakla beraber, genel sonuçların dünya literatürü ile uyumlu olması ileride daha yüksek hasta sayısı ile yapılacak olan çalışmalarda bu faktörün ülkemiz için ne derecede önemli olduğunu ortaya çıkarabilecektir.…”

Section: Discussionunclassified

“…G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Lokalize prostat kanseri nedeniyle 2003 ve RT alan 39 (%46,5) olgunun tedavi kararı ve memnuniyetleri ile tedavi sonrası ilişkili parametreleri 17 sorudan oluşan bir form ile değerlendirilmiş ve her iki hasta grubunun verileri birbiriyle karşılaştırılmıştır. B Bu ul lg gu ul la ar r: : RT ve RRP uygulanan hastaların ortalama yaşı sırası ile 72,12 ±5,41 ve 62,63 ±8,46 yıldır (p<0,001).…”

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Patient Perception and Treatment Satisfaction Related to Curative Therapies in Localized Prostate Cancer

Alkibay¹,

Acar²,

Sözen³

et al. 2012

Turkiye Klinikleri J Med Sci

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1043Lokalize Prostat Kanserinde Uygulanan Küratif Tedaviler ile İlgili Hasta Algılaması ve Tedavi Memnuniyeti Ö ÖZ ZE ET T A Am ma aç ç: : Lokalize prostat kanseri nedeniyle radikal prostatektomi (RRP) veya eksternal radyoterapi (RT) uygulanan hastaların, karşılaştırılmalı olarak tedavilerini algılamalarını ve memnuniyetlerini değerlendirmek. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Lokalize prostat kanseri nedeniyle 2003 ve RT alan 39 (%46,5) olgunun tedavi kararı ve memnuniyetleri ile tedavi sonrası ilişkili parametreleri 17 sorudan oluşan bir form ile değerlendirilmiş ve her iki hasta grubunun verileri birbiriyle karşılaştırılmıştır. B Bu ul lg gu ul la ar r: : RT ve RRP uygulanan hastaların ortalama yaşı sırası ile 72,12 ±5,41 ve 62,63 ±8,46 yıldır (p<0,001). Hastaların 68(%81)'i uygulanan tedavilerden oldukça veya mükemmel derecede tatmin olduklarını belirtirken, RRP grubunda 14 (%31,1) ve RT grubunda ise 17 (43,6) hasta kanserlerinin tamamen tedavi edilmediğini düşünmekte idi (p=0,200). Hastalarda tedavi sonrası oluşan bağırsak problemleri, inkontinans ve empotans komplikasyonları değerlendirildiğinde sadece bağırsak problemlerinin RT grubunda RRP grubuna göre daha fazla olduğu gözlendi (p=0,036). RT grubunda 14 (%31,9) ve RRP grubunda 21 (%46,7) olgu tedavi sonrası genel sağlık durumlarını çok iyi veya mükemmel olarak değerlendirdi (p=0,811). S So on nu uç ç: : Lokalize prostat kanseri nedeniyle RT veya RRP uygulanan hastaların çoğunluğu bu tedavilerden memnun kalmaktadır.A An na ah ht ta ar r K Ke el li im me el le er r: : Prostatektomi; radyoterapi, uyumlu; hasta memnuniyeti; kabul; prostat tümörleri A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To assess and compare the treatment perception and satisfaction of the patients who underwent radical retropubic prostatectomy (RRP) and external beam radiotherapy (RT) for localized prostate cancer. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : The treatment decision, satisfaction and post-treatment parameters of 45 (53.5%) and 39 (46.5%) patients who underwent RRP and RT, respectively for localized prostate cancer between 2003 and 2008 were evaluated with a form consisting of 17 questions. The data obtained from these two groups were compared with each other. R Re es su ul lt ts s: : The mean age of the patients who underwent RT and RRP were 72.12 ±5.41 and 62.63 ±8.46 years, respectively (p<0.001). Of patients, 68 (81%) declared that they were mostly satisfied with their treatment modalities. Fourteen (31.1%) cases in RRP and 17 (43.6%) cases in RT group thought that their cancer was not completely treated (p=0.200). When impotence, incontinence and bowel problems following both treatment modalities were considered, only bowel problems were detected more frequently in RT group group compared to RRP group (p=0.036). Fourteen (35.9%) patients in RT group and 21 (46.7%) patients in RRP group declared their overall health status as very good or perfect after the treatment (p=0.811). C Co on nc cl lu us si io on n: : The vast m...

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Patient satisfaction with treatment decisions for clinically localized prostate carcinoma. Results from the Prostate Cancer Outcomes Study

Cited by 146 publications

References 26 publications

Quality of life after radical prostatectomy in Japanese men: A 5‐Year follow up study

Quality of life after radical prostatectomy in Japanese men: A 5‐Year follow up study

Impact of androgen deprivation therapy on sexual function

Patient Perception and Treatment Satisfaction Related to Curative Therapies in Localized Prostate Cancer

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