2016
DOI: 10.5301/ijao.5000504
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Patient-Specific Modeling of Multicompartmental Fluid and Mass Exchange during Dialysis

Abstract: The peculiarity of the proposed model is the possibility it offers to perform a real-time simulation enabling quantitative appraisal of hematochemical quantities whose direct measurement is prohibitive. These will be beneficial to dialysis therapy planning, reducing intradialysis complications and improving patients' quality of life.

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Cited by 21 publications
(34 citation statements)
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“…The only available work that includes a patient-specific characterization of solute kinetics in HD is that of Casagrande et al, 9 where the estimates have been obtained by minimizing a weighted least-square criterion function of the differences between clinical data and model predictions. However, in the context of HD, this approach shows two limitations.…”
Section: Dialysis Modelingmentioning
confidence: 99%
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“…The only available work that includes a patient-specific characterization of solute kinetics in HD is that of Casagrande et al, 9 where the estimates have been obtained by minimizing a weighted least-square criterion function of the differences between clinical data and model predictions. However, in the context of HD, this approach shows two limitations.…”
Section: Dialysis Modelingmentioning
confidence: 99%
“…We consider the multi-compartment kinetic model of Casagrande et al 9 and assume that the customization is given in terms of patient-specific model parameters, while the structure of the model remains the same for all HD patients. An overview of the model is provided below; further details can be found in Casagrande et al 9 This model allows to evaluate, for the entire duration of a HD treatment, the temporal trend of the blood concentration for different plasmatic electrolytes and breakdown products (defined as solutes in the following), together with the temporal trend of blood volume.…”
Section: Multi-compartment Kinetic Modelmentioning
confidence: 99%
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