Patient specific total temporomandibular joint reconstruction: A review of biomaterial, designs, fabrication and outcomes

Mehrotra, Divya; Kumar, Sumit; Mehrotra, Pankhuri; Khanna, Ranjana S.; Khanna, Vikram; Eggbeer, Dominic; Evans, Peter

doi:10.1016/j.jobcr.2021.02.014

Cited by 18 publications

(7 citation statements)

References 68 publications

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“…Growing developments in synthetic biomaterials show promise for replacing autografts in oral-maxillofacial bone tissue reconstruction applications [ 1 , 4 , 5 ]. With the evolution of personalized medicine, synthetic biomaterials have been increasingly used in the reconstruction of oral-maxillofacial bone defects through the advanced applications of cone-beam computed tomography combined with three-dimensional (3D) printing technology [ 6 , 7 ]. Biomaterials customized by 3D printing technology for oral-maxillofacial bone defects could also save more time during surgery.…”

Section: Introductionmentioning

confidence: 99%

Vascularized bone regeneration accelerated by 3D-printed nanosilicate-functionalized polycaprolactone scaffold

Xiao

et al. 2021

Regenerative Biomaterials

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Critical oral-maxillofacial bone defects, damaged by trauma and tumors, not only affect the physiological functions and mental health of patients but are also highly challenging to reconstruct. Personalized biomaterials customized by 3D printing technology have the potential to match oral-maxillofacial bone repair and regeneration requirements. Laponite (LAP) nanosilicates have been added to biomaterials to achieve biofunctional modification owing to their excellent biocompatibility and bioactivity. Herein, porous nanosilicate-functionalized polycaprolactone (PCL/LAP) was fabricated by 3D printing technology, and its bioactivities in bone regeneration were investigated in vitro and in vivo. In vitro experiments demonstrated that PCL/LAP exhibited good cytocompatibility and enhanced the viability of bone marrow mesenchymal stem cells (BMSCs). PCL/LAP functioned to stimulate osteogenic differentiation of BMSCs at the mRNA and protein levels and elevated angiogenic gene expression and cytokine secretion. Moreover, BMSCs cultured on PCL/LAP promoted the angiogenesis potential of endothelial cells by angiogenic cytokine secretion. Then, PCL/LAP scaffolds were implanted into the calvarial defect model. Toxicological safety of PCL/LAP was confirmed, and significant enhancement of vascularized bone formation was observed. Taken together, 3D-printed PCL/LAP scaffolds with brilliant osteogenesis to enhance bone regeneration could be envisaged as an outstanding bone substitute for a promising change in oral-maxillofacial bone defect reconstruction.

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Section: Introductionmentioning

confidence: 99%

Vascularized bone regeneration accelerated by 3D-printed nanosilicate-functionalized polycaprolactone scaffold

Xiao

et al. 2021

Regenerative Biomaterials

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“…By the use of wear-resistant materials (material combinations) such as UHMWPE for the fossa and cobalt–chromium–molybdenum or titanium alloy forming the condyle component, most of these disadvantages have been significantly reduced. The osteosynthesis screws used are made of titanium alloy by all well-known manufacturers [ 5 ]. And although current guidelines of European professional societies mention the risks of screw loosening and fracture, especially in the case of strong muscular hyperactivity [ 6 ], these events are extremely rare to not described at all in the literature for patient-specific/custom-made prostheses/implants [ 1 , 5 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…The osteosynthesis screws used are made of titanium alloy by all well-known manufacturers [ 5 ]. And although current guidelines of European professional societies mention the risks of screw loosening and fracture, especially in the case of strong muscular hyperactivity [ 6 ], these events are extremely rare to not described at all in the literature for patient-specific/custom-made prostheses/implants [ 1 , 5 , 7 ]. PSI-TJRs are believed to allow less micromovement at the implant–bone interface due to their higher fitting accuracy based on high-resolution imaging techniques.…”

Section: Discussionmentioning

confidence: 99%

Technical report and rare case description—patient-specific spacer made of bone cement for the revision of a PSI-TMJ fossa after screw fracture

Thiem

Al‐Nawas

Kämmerer

2021

Journal of Surgical Case Reports

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Total alloplastic temporomandibular joint replacement (TMJ-TJR) has once again become the focus of therapy for end-stage destroyed joints. Although material quality has increased significantly in terms of service life and wear, problems occur even with patient-specific (PSI) prostheses. Here, mainly the ramus components are affected and an occurrence of screw loosening or fractures in the area of the fossa of stock joints is rare and has not yet been described for patient-specific (PSI) components. Although very rare, such events pose a great challenge to both practitioners and affected patients, especially in the case of PSI components, not least due to the long time required for new fabrication. The case report shows a non-described screw fracture of a PSI-TMJ fossa and the first description of a temporary revision using a PSI-TMJ fossa made of bone cement.

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“…La literatura ha reportado grandes ventajas como reducción del tiempo operatorio, la visualización de componentes neurovasculares, lo que reduce el riesgo de su daño, y resultados altamente predecibles con estabilidad esquelética y oclusal 7 . Sus desventajas se asocian a problemas de longevidad debido al desgaste o falla del material, hipersensibilidad del material y alto costo 8 .…”

Section: Discussionunclassified

Corrección de microsomía hemifacial con prótesis de articulación temporomandibular con extensión a arco cigomático y cirugía ortognática

Jácome¹,

Arteaga²,

Santofimio³

et al. 2021

j.maxilo

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Patient specific total temporomandibular joint reconstruction: A review of biomaterial, designs, fabrication and outcomes

Cited by 18 publications

References 68 publications

Vascularized bone regeneration accelerated by 3D-printed nanosilicate-functionalized polycaprolactone scaffold

Vascularized bone regeneration accelerated by 3D-printed nanosilicate-functionalized polycaprolactone scaffold

Technical report and rare case description—patient-specific spacer made of bone cement for the revision of a PSI-TMJ fossa after screw fracture

Corrección de microsomía hemifacial con prótesis de articulación temporomandibular con extensión a arco cigomático y cirugía ortognática

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