Patient Tolerability With Office Transperineal Biopsy Using a Reusable Needle Guide

Wertheimer, Stephen; Budzyn, Jeffrey; Perkins, Sara; Borchert, Alex; Rogers, Craig G.; Patel, Amit

doi:10.1016/j.urology.2021.05.018

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…EZU-PA3U-FUJIFILM and PrecisionPoint-BXTAccelyon). 55 , 56 This freehand method utilizes the mobility of the perineal skin and ischiorectal fat, allowing for freedom of movement and access to all parts of the prostate. 57 …”

Section: Transperineal Biopsymentioning

confidence: 99%

Shifting to transperineal prostate biopsy: A narrative review

Chung,

Hong

2023

Prostate International

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Section: Transperineal Biopsymentioning

confidence: 99%

Shifting to transperineal prostate biopsy: A narrative review

Chung,

Hong

2023

Prostate International

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A cost-effective transperineal prostate biopsy method utilizes the original transrectal setting

Wu,

Tung,

et al. 2023

Int Urol Nephrol

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Tolerability of Transperineal Prostate Biopsy Under Local Anaesthetic Using Pre-Emptive Over-the-Counter Analgesia: An Interventional Study in Patients with Abnormal Clinical Prostate Findings

Wang,

Xu,

Cheng

et al. 2024

SIUJ

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Objective: Transperineal prostate (TP) biopsy is the key diagnostic tool for evaluating prostate cancer and is feasible under local anaesthetic (LA) alone. However, concerns about its tolerability encourage use of a multimodal analgesia approach. Pre-emptive over-the-counter analgesia with LA may provide a simple and low-risk option. The objective of this study was to investigate the effects of over-the-counter analgesia on TP biopsies conducted under LA. Methods: This interventional single-centre study investigated 160 participants who undertook a TP biopsy under LA, with and without pre-emptive analgesia (1 g of paracetamol and 400 mg of ibuprofen). Pain tolerability was measured using a visual analogue scale (VAS) at three procedural points (probe insertion, LA infiltration, and biopsy); an overall average VAS score was subsequently calculated. The abstracted secondary variables include patient details (age, prostate size, and PSA level), biopsy details (number of cores and volume of LA used), and preferability for LA use in future TP biopsies. An inferential statistical analysis was performed using Wilcoxon’s Rank Sum non-parametric test, Pearson’s test of correlation, and Pearson’s Chi-squared test. Results: The groups were comparable in age, prostate size, and PSA level. Median VAS scores were consistently lower in the intervention cohort, but without statistical significance. A higher volume of LA was associated with lower overall VAS (p = 0.03). LA was strongly preferred over GA for hypothetical future TP biopsies in both cohorts. Conclusions: Pre-emptive analgesia does not significantly improve tolerability of TP biopsy under LA. Our study substantiates evidence that TP biopsy is generally well tolerated under LA and preferred over GA.

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Patient Tolerability With Office Transperineal Biopsy Using a Reusable Needle Guide

Cited by 3 publications

References 5 publications

Shifting to transperineal prostate biopsy: A narrative review

Shifting to transperineal prostate biopsy: A narrative review

A cost-effective transperineal prostate biopsy method utilizes the original transrectal setting

Tolerability of Transperineal Prostate Biopsy Under Local Anaesthetic Using Pre-Emptive Over-the-Counter Analgesia: An Interventional Study in Patients with Abnormal Clinical Prostate Findings

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