Background: Physician communication with patients is a key aspect of excellent care. Scant evidence exists to inform best practice for physician communication in patients diagnosed with pulmonary embolism and deep vein thrombosis, collectively referred to as venous thromboembolism (VTE). The aim of this study was to summarize the existing literature on best practices for communication between healthcare providers and patients newly diagnosed with VTE. Methods: We performed a scoping review of the extant literature on best practice for physician patient communication and the diagnosis and management of VTE. Manuscripts on communication between healthcare professionals and patients with acute vascular diseases, including VTE, were eligible. Two authors independently reviewed titles, and consensus determined article inclusion. The manuscripts were further categorized into two main categories: best practice in communication and unmet needs in communication. Data aggregation was achieved by a modified thematic synthesis. Results: Among 345 initial publications, 22 manuscripts met inclusion criteria with 11 that addressed VTE, five pulmonary embolism, four deep vein thrombosis, one atrial fibrillation, and one acute coronary syndrome. Eleven manuscripts addressed communication of VTE diagnosis, while 12 focused on communication of VTE treatment. Eleven manuscripts identified unmet communication needs, and 14 addressed best practice. Our review shows that good communication surrounding the VTE diagnosis and treatment can enhance satisfaction while suboptimal communication can incur emotional, cognitive, behavioral, social, and health- systems adverse effects. Conclusion: Scant literature guides best practices for communicating VTE diagnosis and treatment. Further research is necessary to establish practices for improving communication with VTE patients.