Acknowledgements: Thank you to Rebecca Porter (School of Health and SocialCare, University of Lincoln) for her support with data extraction for this project.Sirdifield led the study and contributed to all stages of the analysis and write-up Chipchase contributed to all stages of the analysis and write up Owen read and commented on drafts of the paper and model, and proof read the final version Siriwardena had the idea for this study, and has contributed to the design, conception, analysis and drafts of the paper (including final revisions).
AbstractBackground: Benzodiazepines and z-drugs are used to treat complaints like insomnia, anxiety and pain. These drugs are recommended for short-term use only, but many studies report long-term use, particularly in older people.Objective: To identify and synthesise qualitative studies exploring patients' experiences and perceptions of receiving benzodiazepines and z-drugs, and through this identify factors which perpetuate use of these drugs, and strategies for achieving safer prescribing.Methods: A systematic search of six databases for qualitative studies exploring patients' experiences and perceptions of primary care benzodiazepine and z-drug prescribing published between January 2000 and April 2014 in a European language, and conducted in Europe, the United States, Australia or New Zealand. Reference lists of included papers were also searched. Study quality was assessed using the Critical Appraisal Skills Programme qualitative checklist. Findings were synthesised using thematic synthesis.Results: Nine papers were included and seven analytical themes were identified relating to patients' experiences and perceptions and, within that, strategies for safer prescribing of benzodiazepines and z-drugs: 1) patients' negative perceptions of insomnia and its impact, 2) failed self-care strategies, 3) triggers to medical helpseeking, 4) attitudes towards treatment options and service provision, 5) varying patterns of use, 6) withdrawal, 7) reasons for initial or ongoing use.
Conclusions:Inappropriate use and prescribing of benzodiazepines and z-drugs is perpetuated by psychological dependence, absence of support and patients' denial/lack of knowledge of side-effects. Education strategies, increased availability of alternatives, and targeted extended dialogue with patients could support safer prescribing.
Key Points Long-term use of benzodiazepines and z-drugs can have adverse consequences, but research reports long-term use, particularly in older people 4 We identified seven themes from published qualitative research which add to our understanding of patients' experiences and perceptions of seeking and using these drugs, and factors perpetuating their use Safer prescribing could be supported through education strategies for patients and healthcare professionals, increased availability of alternatives, and targeted extended dialogue between patients and healthcare professionals 5