Patientsʼ attitudes to medicines and adherence to maintenance treatment in inflammatory bowel disease

Horne, Rob; Parham, Rhian; Driscoll, Richard; Robinson, Andrew

doi:10.1002/ibd.20846

Cited by 244 publications

(261 citation statements)

References 37 publications

Supporting

Mentioning

237

Contrasting

Unclassified

Order By: Relevance

“…This finding, which supports an association between beliefs about PBM and poor adherence, is consistent with studies which have explored this relationship in other chronic illness groups (e.g. Aikens et al, 2005;Horne et al, 2001;Horne and Weinman, 2002;Horne et al, 2004;Horne et al, 2007;Horne et al, 2009;Hunot et al, 2007). Furthermore, the creation of attitudinal groups based on patient's beliefs about PBM offered further insight into the relationship between treatment beliefs and adherence behaviour.…”

supporting

confidence: 89%

Profiling patient attitudes to phosphate binding medication: A route to personalising treatment and adherence support

Chater

Parham

Riley

et al. 2014

Psychology & Health

Self Cite

View full text Add to dashboard Cite

Objective: Nonadherence to phosphate binding medication (PBM) compromises the efficacy of treatment for chronic kidney disease (CKD), but its causes are poorly understood. This study sought to explore patient attitudes towards PBM and to evaluate the utility of the Necessity-Concerns Framework for understanding adherence to PBM. Design: A sample of two hundred and twenty-one dialysis patients currently prescribed PBM were surveyed from eight UK renal units. Main Outcome Measures: Demographic data and clinical information, alongside the Beliefs about Medication Questionnaire (BMQ) and the Medication Adherence Report Scale (MARS) were reported. Results: Low adherence to PBM was predicted by reduced beliefs in personal need for PBM (OR = .34; 95% CI: .14-.83; p < .05), and increased concerns about PBM (OR = 3.17; 95% CI: 1.87-5.37; p < .001). Patients were categorised into attitudinal groups based on their beliefs about PBM and being 'skeptical' of PBM (low necessity beliefs, high concerns) was most associated with low adherence. Conclusion:Strategies to improve adherence to PBM should aim to elicit and address patients' beliefs about their personal need for PBM and their concerns about this medication.

show abstract

supporting

confidence: 89%

Profiling patient attitudes to phosphate binding medication: A route to personalising treatment and adherence support

Chater

Parham

Riley

et al. 2014

Psychology & Health

Self Cite

View full text Add to dashboard Cite

show abstract

“…Our findings thus concur with findings from research in other conditions such as asthma [19], and depression [27], where the experience of concrete symptoms has been found to influence individuals' decisions about commencing medication.…”

Section: Comparison With Other Literaturesupporting

confidence: 89%

“…The observation that insulin was perceived as a 'last resort' treatment presents a major challenge in the clinical management and treatment of Type 2 diabetes; poor glycaemic control may not immediately manifest symptoms of complications, thereby reducing individuals' perceptions of the necessity [19] of starting insulin therapy in a timely manner. Our findings thus concur with findings from research in other conditions such as asthma [19], and depression [27], where the experience of concrete symptoms has been found to influence individuals' decisions about commencing medication.…”

Section: Comparison With Other Literaturementioning

confidence: 99%

“…This finding, based on participants' accounts, fits with findings from our previous study, conducted in a similar setting, in which healthcare professionals perceived the influence of 'other people' as being accentuated amongst their South Asian patients [8]. Other authors have also highlighted the importance of contextual influences such as families and community networks [26].The observation that insulin was perceived as a 'last resort' treatment presents a major challenge in the clinical management and treatment of Type 2 diabetes; poor glycaemic control may not immediately manifest symptoms of complications, thereby reducing individuals' perceptions of the necessity [19] of starting insulin therapy in a timely manner. Our findings thus concur with findings from research in other conditions such as asthma [19], and depression [27], where the experience of concrete symptoms has been found to influence individuals' decisions about commencing medication.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Concerns and perceptions about necessity in relation to insulin therapy in an ethnically diverse UK population with Type 2 diabetes: a qualitative study focusing mainly on people of South Asian origin

et al. 2014

View full text Add to dashboard Cite

Aim:To explore attitudes towards insulin acceptance in an ethnically diverse population of people with Type 2 diabetes. Methods: We conducted semi-structured interviews using a topic guide based on a literature review and findings from our previous study which explored the perspectives of healthcare professionals about insulin initiation and management. Analysis of data involved undertaking an abductive approach in response to emerging themes. Results: Participants discussed not only their concerns about insulin therapy, but also their views and beliefs about the necessity of insulin. Their attitudes to accepting insulin could be mapped into four main typologies. These fitted with an attitudinal scale based on the Necessity-Concerns Framework, described in the medication adherence literature, comprising four attitudes: accepting, sceptical, ambivalent and indifferent. Decisions about accepting insulin involved balancing concerns (such as needle-size) against perceived necessity of insulin (generally, inadequacy of oral medication). South Asian and White British participants had similar concerns, but these were sometimes enhanced in South Asians, due to the influence of negative views and experiences of other insulin users. Conclusions: When discussing insulin with people with Type 2 diabetes, healthcare providers need to ensure that they explore and contribute to patients' understanding and interpretation of the necessity of insulin as well as discussing their concerns. Furthermore, they should be aware of how an individual's social context can influence their perceptions about the necessity of insulin as well as concerns, and that this influence may be more enhanced in some South Asian populations. Word count: 244 Correspondence to: Naina Patel. E-mail: np89@le.ac.uk What's new?• This is the first time the Necessity and Concerns Framework drawn from the medical adherence literature has been used to explore decisions to commence insulin therapy in an ethnically diverse sample of people with Type 2 diabetes.• This study offers a practical insight on why it is important to elicit beliefs about the necessity of insulin therapy as well as people's concerns to help address the reluctance of some people with Type 2 diabetes to commence insulin therapy in a timely way.2 IntroductionApproximately 50% of people with Type 2 diabetes will at some point need to commence insulin therapy [1] in order to achieve or maintain good levels of blood glucose control. Good glycaemic control can help to reduce or prevent the development of diabetes associated complications as shown by the 10 year post-trial follow up data from the United Kingdom Prospective Diabetes Study [2]. This showed that good glycaemic control continued to confer benefits; in the sulfonylurea-insulin group, for example, there were relative reductions of 13% and 24% in the risk of diabetes-related death and microvascular complications respectively. Additionally, research modelling has shown that if insulin is commenced according to management guidelines there ...

show abstract

“…43 Studies in young adults with diabetes and renal transplant recipients using objective markers of non-adherence 49,50 confirm lower adherence to maintenance therapies in young adults compared with adults. Allowing for the small number of patients who were non-adherent in this study, there were no differences in the proportions of non-adherent or adherent, adult or adolescent patients' responses to the individual questions of the MMAS-8 (data not shown).…”

mentioning

confidence: 97%

Factors associated with thiopurine non-adherence in patients with inflammatory bowel disease

Goodhand

Kamperidis

Sirwan

et al. 2013

Aliment Pharmacol Ther

View full text Add to dashboard Cite

show abstract

Patientsʼ attitudes to medicines and adherence to maintenance treatment in inflammatory bowel disease

Abstract: The way in which patients judge their personal need for MT relative to their concerns about MT can be a significant barrier to adherence. Interventions to facilitate optimal adherence to MT for IBD should address such perceptual barriers.

Cited by 244 publications

References 37 publications

Profiling patient attitudes to phosphate binding medication: A route to personalising treatment and adherence support

Profiling patient attitudes to phosphate binding medication: A route to personalising treatment and adherence support

Concerns and perceptions about necessity in relation to insulin therapy in an ethnically diverse UK population with Type 2 diabetes: a qualitative study focusing mainly on people of South Asian origin

Factors associated with thiopurine non-adherence in patients with inflammatory bowel disease

Contact Info

Product

Resources

About