Patients' attitudes to xenotransplantation

Mohacsi, P; Je, Thompson; Nicholson, J D; Dj, Tiller

doi:10.1016/s0140-6736(05)62938-8

Cited by 36 publications

(27 citation statements)

References 4 publications

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“…Xenotransplantation is proposed as an alternative or additional approach for coping with the global shortage of human organs for allotransplantation and as a treatment for diseases with no other effective therapeutic options [1–3,6,7]. The general attitude of people involved in xenotransplantation and xenotransplantation research is positive, and they foresee a future in which animals will routinely provide organs for humans [24]. Although the perceived scientific aim is to reduce suffering and improve human health worldwide, xenotransplantation raises important issues regarding its acceptability for both biomedical and ethical reasons [13–15].…”

Section: Discussionmentioning

confidence: 99%

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Understanding of and attitudes to xenotransplantation: a survey among Italian university students

Bona¹,

Canova²,

Rumiati³

et al. 2004

Xenotransplantation

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chi-squared, Pearson's test; P-values <0.05 were considered significant. A total of 585 of 602 (97.2%) students completed the questionnaire (132 males, 453 females, mean age 20.4, range 19 to 43 yr). They were on courses in Medicine (33.85%), Agriculture (5.98%), Veterinary Medicine (11.45%), Psychology (18.46%) and Educational Sciences (30.26%). As for their previous schooling, they came from classical or scientific high school (58.3%), technical college (14.7%), language college (6.3%), teacher training college (11.9%) or others (8.8%). Concerning their religious beliefs, 83% were Catholics, and 56.2% defined themselves as practising Catholics. Eighty-eight percentage of the students knew of the possibility of animal organs being transplanted into humans and 77.9% of them approved of this idea. When grouped according to gender and education, a higher proportion of students approving of xenotransplantation were male (P = 0.017) and had attended classical or scientific high school (P = 0.011). Disapproval for moral, ethical or religious reasons was higher among practising than among non-practising Catholics; the latter rejected xenotransplantation more for immunological and infectious reasons (P = 0.014). As for the type of university course, a higher proportion of students approving of xenotransplantation attended science courses (Veterinary Medicine, Agriculture and Medicine vs. Educational Sciences and Psychology) (P = 0.013). University students generally approved of xenotransplantation. Male gender and a high-school education were associated with a greater acceptance of xenotransplantation. Practising vs. non-practising Catholics reported significantly different reasons for any disapproval of xenotransplantation. The choice of a science rather than an arts faculty at university was more strongly associated with a positive opinion on xenotransplantation.

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Section: Discussionmentioning

confidence: 99%

“…A survey among intensive‐care staff, on the other hand, revealed a negative opinion, with 66% of acute‐care nurses reportedly opposed to xenotransplantation [23]. A report on 113 patients with renal failure who were potential or actual transplant recipients showed that only 42% of them were willing to accept an animal donor [24].…”

Section: Introductionmentioning

confidence: 99%

Understanding of and attitudes to xenotransplantation: a survey among Italian university students

Bona¹,

Canova²,

Rumiati³

et al. 2004

Xenotransplantation

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“…Mohacsi et al. performed a study on the acceptance of xenotransplantation among patients treated by hemodialysis (n=58), peritoneal dialysis (n=31) and transplantation (n=24) [10]. According to the authors, there were no significant differences in the responses of the three patient groups.…”

Section: Discussionmentioning

confidence: 99%

Xenotransplantation public perceptions: rather cells than organs

Persson

Ranstam

et al. 2003

Xenotransplantation

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“…Although attitudes of the general population and of medical professionals toward xenotransplantation are important, it is the attitude of potentially affected patients that must be considered in the development of xenotransplantation. The acceptance of xenografts by patients has been studied by few groups, who reported acceptance rates for xenogeneic kidneys between 42% and 78% [10,11,12]. These studies are, however, of limited value, since they give no information about acceptance of extra-renal organs, about factors contributing to either acceptance or disapproval, and about specific hopes and concerns of patients with regard to xenotransplantation.…”

Section: Introductionmentioning

confidence: 99%