Patients’ Preference Between DPP4i and SGLT2i for Type 2 Diabetes Treatment: A Cross-Sectional Evaluation

Gil, José E Costa; Garnica-Cuellar, Juan C.; Terns, Paula Perez; Ferreira‐Hermosillo, Aldo; Canto, José Antonio Cetina; Perez, Ángel Alfonso Garduño; Martínez, Pedro Mendoza; Rista, Lucas; Sosa-Caballero, Alejandro; Vázquez-Méndez, Estefanía; Gallegos, Luis Fernando Tejado; Chen, Hungta; Elizalde, Agustina; Tomatis, Virginia B

doi:10.2147/ppa.s355638

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…Patient preferences and WTP for improvements in diabetes treatment have been assessed using Discrete Choice Experiments (DCEs) in the US [23], the Netherlands [24] and Denmark [9], but few published studies have used DCEs to measure diabetes care preferences in low-and middle-income countries (LMICs) [25]. These specialized surveys present participants with hypothetical scenarios composed of a series of multi-alternative choice profiles.…”

Section: Introductionmentioning

confidence: 99%

Identifying patient preferences for diabetes care: A protocol for implementing a discrete choice experiment in Samoa

Rivara,

Galárraga,

Selu

et al. 2023

PLoS ONE

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In Samoa, adult Type 2 diabetes prevalence has increased within the past 30 years. Patient preferences for care are factors known to influence treatment adherence and are associated with reduced disease progression and severity. However, patient preferences for diabetes care, generally, are understudied, and other patient-centered factors such as willingness-to-pay (WTP) for diabetes treatment have never been explored in this setting. Discrete Choice Experiments (DCE) are useful tools to elicit preferences and WTP for healthcare. DCEs present patients with hypothetical scenarios composed of a series of multi-alternative choice profiles made up of attributes and levels. Patients choose a profile based on which attributes and levels may be preferable for them, thereby quantifying and identifying locally relevant patient-centered preferences. This paper presents the protocol for the design, piloting, and implementation of a DCE identifying patient preferences for diabetes care, in Samoa. Using an exploratory sequential mixed methods design, formative data from a literature review and semi-structured interviews with n = 20 Samoan adults living with Type 2 diabetes was used to design a Best-Best DCE instrument. Experimental design procedures were used to reduce the number of choice-sets and balance the instrument. Following pilot testing, the DCE is being administered to n = 450 Samoan adults living with diabetes, along with associated questionnaires, and anthropometrics. Subsequently, we will also be assessing longitudinally how preferences for care change over time. Data will be analyzed using progressive mixed Rank Order Logit models. The results will identify which diabetes care attributes are important to patients (p < 0.05), examine associations between participant characteristics and preference, illuminate the trade-offs participants are willing to make, and the probability of uptake, and WTP for specific attributes and levels. The results from this study will provide integral data useful for designing and adapting efficacious diabetes intervention and treatment approaches in this setting.

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