Patients with chronic fatigue syndrome and accurate feeling-of-knowing judgments

Lakein, Debora; Fantie, Bryan D.; Grafman, Jordan; Ross, Sharon; O'Fallon, Ann; Dale, Janet K.; Straus, Stephen E.

doi:10.1002/(sici)1097-4679(199711)53:7<635::aid-jclp1>3.0.co;2-h

Cited by 7 publications

(3 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This has been related to a tendency to underestimate actual performance relative to expectations of ‘normal’ performance 35. Contrary to this hypothesis, two studies observed normal estimations of memory abilities and corresponding objective performance 30 60…”

Section: Results: Evidence For Abnormal Cognition In Fm Cfs and Fndmentioning

confidence: 93%

“…Prominent reported difficulties in memory,25 38 124 attention/concentration,25 124 information processing124 and general cognitive function30 38 131 143 contrast with little or no deficit on objective assessment 25 30 38 124 131 143. Notably, prominent symptoms have been associated with impairment in only a minority of patients 28.…”

Section: Results: Evidence For Abnormal Cognition In Fm Cfs and Fndmentioning

confidence: 99%

See 1 more Smart Citation

A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome: systematic review

Teodoro

Edwards

Isaacs

2018

J Neurol Neurosurg Psychiatry

176

159

View full text Add to dashboard Cite

BackgroundFunctional cognitive disorder (FCD) describes cognitive dysfunction in the absence of an organic cause. It is increasingly prevalent in healthcare settings yet its key neuropsychological features have not been reported in large patient cohorts. We hypothesised that cognitive profiles in fibromyalgia (FM), chronic fatigue syndrome (CFS) and functional neurological disorders (FNDs) would provide a template for characterising FCD.MethodsWe conducted a systematic review of studies with cognition-related outcomes in FM, CFS and FND.ResultsWe selected 52 studies on FM, 95 on CFS and 39 on FND. We found a general discordance between high rates of subjective cognitive symptoms, including forgetfulness, distractibility and word-finding difficulties, and inconsistent objective neuropsychological deficits. Objective deficits were reported, including poor selective and divided attention, slow information processing and vulnerability to distraction. In some studies, cognitive performance was inversely correlated with pain, exertion and fatigue. Performance validity testing demonstrated poor effort in only a minority of subjects, and patients with CFS showed a heightened perception of effort.DiscussionThe cognitive profiles of FM, CFS and non-cognitive FND are similar to the proposed features of FCD, suggesting common mechanistic underpinnings. Similar findings have been reported in patients with mild traumatic brain injury and whiplash. We hypothesise that pain, fatigue and excessive interoceptive monitoring produce a decrease in externally directed attention. This increases susceptibility to distraction and slows information processing, interfering with cognitive function, in particular multitasking. Routine cognitive processes are experienced as unduly effortful. This may reflect a switch from an automatic to a less efficient controlled or explicit cognitive mode, a mechanism that has also been proposed for impaired motor control in FND. These experiences might then be overinterpreted due to memory perfectionism and heightened self-monitoring of cognitive performance.

show abstract

Section: Results: Evidence For Abnormal Cognition In Fm Cfs and Fndmentioning

confidence: 93%

Section: Results: Evidence For Abnormal Cognition In Fm Cfs and Fndmentioning

confidence: 99%

A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome: systematic review

Teodoro

Edwards

Isaacs

2018

J Neurol Neurosurg Psychiatry

176

159

View full text Add to dashboard Cite

show abstract

“…The provision of recognition measures does not appear to enhance retrieval. It also does not appear to be the case that the deficit is attributable to metamemory processes (Lakein et al, 1997).…”

mentioning

confidence: 94%

A neuropsychological study of the chronic fatigue syndrome: Support for a deficit in memory function independent of depression

Crowe

Casey

1999

Australian Psychologist

View full text Add to dashboard Cite

Well‐controlled studies of the cognitive status of chronic fatigue syndrome (CFS) participants are rare. This study aimed to examine the deficit in cognitive functioning in CFS after the effects of depression had been controlled. Twenty‐six CFS sufferers and twenty‐six matched control participants were compared on the Chronic Fatigue Symptom Checklist, the Illness Behaviour Questionnaire, the Beck Depression Inventory, Performance IQ from the WAIS‐R, the Rey Auditory Verbal Learning Test, the Controlled Oral Word Association Test, and a series of measures of attention and concentration tasks including the Digit Span Test, the Paced Auditory Serial Addition Test, and Simple and Choice Reaction. In these participants with a medically confirmed diagnosis of CFS, there is a high endorsement of cognitive‐related items on self‐report measures. There is also a significantly higher level of depressive and hypochondriacal mentation. However, once the effects of depressive mentation had been partialled out, a significantly lower performance on the learning across trials of the RAVLT persisted. This indicates that a pattern of impairment characteristic of this group has been observed and supports the notion of central nervous system compromise in these participants.

show abstract

The relationship between perceived and objective cognitive functioning in multiple sclerosis

Middleton

Denney

Lynch

et al. 2006

Archives of Clinical Neuropsychology

131

View full text Add to dashboard Cite

The relationship between perceived cognitive functioning and objective cognitive functioning was studied in 221 patients with multiple sclerosis. Perceptions of global cognitive functioning as well as perceptions of performance on specific cognitive tests were assessed. Patients' perceptions of global cognitive functioning in their daily lives were unrelated to their objective performance on the full cognitive test battery. However, patients' perceptions of their performance on specific tasks correlated with their objective performance on those tasks, even though they underestimated their performance on these tasks. The present study also evaluated predictors of patients' perceived cognitive functioning. Depression, anxiety, fatigue, and level of disability predicted perceptions of global cognitive functioning, whereas objective cognitive performance did not. These results add to our understanding of patients' expressed concerns regarding their cognitive functioning in the wake of multiple sclerosis, suggesting that such concerns should be interpreted with caution by clinicians.

show abstract

Patients with chronic fatigue syndrome and accurate feeling-of-knowing judgments

Cited by 7 publications

References 21 publications

A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome: systematic review

A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome: systematic review

A neuropsychological study of the chronic fatigue syndrome: Support for a deficit in memory function independent of depression

The relationship between perceived and objective cognitive functioning in multiple sclerosis

Contact Info

Product

Resources

About