Patients with dyspepsia benefit from eradication of helicobacter pylori if other organic causes for dyspepsia were carefully ruled out

Abstract

HP-infection per se contributes to dyspepsia. 17 of 20 (85%) HP-positive dyspeptic patients improved after HP-eradication, when other potential organic causes for dyspepsia had been ruled out. However, many patients did not completely recover but the symptoms only partly decreased which parallels the persistence of part of the inflammatory infiltration in the gastric mucosa. This emphasizes the importance of HP-gastritis as an organic disease causing dyspeptic symptoms.

Peppermint oil and caraway oil in functional dyspepsia — efficacy unaffected by H. pylori

“…If it is presumed that H. pylori infection has a role in the aetiology of functional dyspepsia, 4–6 we would expect a treatment related to other causes of this disorder to be less effective in H. pylori ‐positive patients if the bacterium is not eradicated simultaneously. In our trial, however, H. pylori ‐positive patients given PCC showed a substantially better treatment response, and there were no interpretable differences in treatment outcome between the two sub‐groups given placebo.…”