Patients with hidradenitis suppurativa have a higher rate of postoperative infections

Jefferson, Itisha S.; Fritsche, Madelaine; Maczuga, Steve; Allen, Steven R.; Nelson, Amanda M.; Kirby, Joslyn S.

doi:10.1016/j.jaad.2022.08.059

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Risk Of Infection With Different Immunobiologicals Used In D...1

Reconstructive Strategies1

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2024

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Cited by 4 publications

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“… 11 In the case of hidradenitis suppurativa, high rates of cutaneous and extracutaneous infections are observed, possibly resulting from the breakdown of the skin barrier and immune system dysregulation. 12 …”

Section: Risk Of Infection With Different Immunobiologicals Used In D...mentioning

confidence: 99%

Infections in the era of immunobiologicals

Romiti,

Hirayama,

Porro

et al. 2024

Anais Brasileiros de Dermatologia

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Section: Risk Of Infection With Different Immunobiologicals Used In D...mentioning

confidence: 99%

Infections in the era of immunobiologicals

Romiti,

Hirayama,

Porro

et al. 2024

Anais Brasileiros de Dermatologia

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“…In general, patients with HS have an increased risk of cutaneous and extracutaneous infection, possibly due to skin barrier disruption and immune dysregulation. These patients have more comorbidities, increasing the risk of postoperative infections, 51 and must receive appropriate perioperative antibiotics. Postsurgical treatment using antibiotics is challenging because most patients develop resistance to the several antibiotics they have received before surgery.…”

Section: Reconstructive Strategiesmentioning

confidence: 99%

Surgical Management of Hidradenitis Suppurativa

Krajewski,

Alsayed,

Capek

et al. 2024

Plastic and Reconstructive Surgery - Global Open

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Hidradenitis suppurativa (HS) is a chronic, relapsing inflammatory disease of the skin, characterized by recurrent draining sinuses and abscesses, predominantly in skin folds carrying terminal hairs and apocrine glands. Treatment for this debilitating disease has been medical management with antibiotics and immune modulators. With the advent of better reconstructive surgical techniques, the role of surgery in the treatment of HS has expanded, from being a last resort to a modality that is deployed earlier. Larger defects can be more easily reconstructed, allowing for a more radical excision of diseased areas. Locoregional flaps, perforator flaps, and propeller flaps that use the fasciocutaneous tissue allow reconstruction of defects with similar tissue, and provide better cosmetic and functional outcomes. They are easy to execute and can be performed even in resource-poor settings with concurrent use of immune modulators and postoperative antibiotics. Hidradenitis can be successfully treated with surgery in early stages as well as severe disease, due to the advances in understanding disease behavior, multidisciplinary care, and advanced reconstructive techniques. Coupled with a multidisciplinary care team, surgery offers a durable, lasting cure for HS, significantly reducing disease morbidity.

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