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“…Thyroid function is assessed by laboratory tests for the detection of TD or monitoring of pre-existing disorders. The most common conditions of thyroid morpho-function can be classified according to altered function: hypothyroidism (thyroid hypofunction) and hyperthyroidism (thyroid hyperfunction); or according to alterations in size: goitre and thyroid nodule (6) function is determined by testing TSH, T4 and T3, although there is much controversy, most professional societies suggest to use TSH to determine thyroid dysfunction in outpatients, provided that the assay used has a functional sensitivity equal to or less than 0.02 mIU/L (6)(7)(8) Subclinical TD is defined as a functional disorder of the thyroid gland, asymptomatic and only detectable by hormonal laboratory tests, especially in middle-aged and older individuals, manifested by altered TSH concentrations and normal serum concentrations of free T3 and T4 (9)(10)(11)(12). Hyperthyroidism (hyperT) is a clinical condition characterized by excessive serum T4 and T3, or both, with suppression of TSH (13).…”
Section: Introductionmentioning
confidence: 99%
“…Thyroid function is assessed by laboratory tests for the detection of TD or monitoring of pre-existing disorders. The most common conditions of thyroid morpho-function can be classified according to altered function: hypothyroidism (thyroid hypofunction) and hyperthyroidism (thyroid hyperfunction); or according to alterations in size: goitre and thyroid nodule (6) function is determined by testing TSH, T4 and T3, although there is much controversy, most professional societies suggest to use TSH to determine thyroid dysfunction in outpatients, provided that the assay used has a functional sensitivity equal to or less than 0.02 mIU/L (6)(7)(8) Subclinical TD is defined as a functional disorder of the thyroid gland, asymptomatic and only detectable by hormonal laboratory tests, especially in middle-aged and older individuals, manifested by altered TSH concentrations and normal serum concentrations of free T3 and T4 (9)(10)(11)(12). Hyperthyroidism (hyperT) is a clinical condition characterized by excessive serum T4 and T3, or both, with suppression of TSH (13).…”
Section: Introductionmentioning
confidence: 99%