Pattern of acute renal failure in a tertiary hospital in the United Arab Emirates

Bernieh, Bassam; Hakim, M. Al; Boobes, Y.; Abuchacra, S.; Dastoor, Hormaz

doi:10.1016/j.transproceed.2004.07.015

Cited by 15 publications

(13 citation statements)

References 18 publications

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“…To evaluate the pattern, management and outcome of acute renal failure (ARF) in a tertiary hospital, Bernieh et al [38] analysed the data of 81 patients admitted with or developing ARF in hospital between January 2002 and June 2003. The 45 men and 36 women were managed either on the ward ( n = 48; 59%) and or in the ICU ( n = 33; 41%).…”

Section: Bibliography With Annotationsmentioning

confidence: 99%

“…Patients treated in the ICU showed a worse prognosis for both patient and renal survival. Age, sex and ethnicity were the demographic data considered but no analysis was done [38]. …”

Section: Bibliography With Annotationsmentioning

confidence: 99%

“…Roughly, of the 26 papers included, nearly half (12) treated comorbidity of depression and mental diseases with NCDS [16-27]. Another set of 11 papers dealt with multimorbidity involving diabetes, CVDs, renal diseases, obesity and metabolic syndrome [28-38]. As indicated earlier, mutimorbidity is naturally associated with older age [13,17,19,20,23,25,27,28],[31,34,36].…”

Section: Bibliography With Annotationsmentioning

confidence: 99%

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Multi-morbidity of non communicable diseases and equity in WHO Eastern Mediterranean countries

Boutayeb

2013

Int J Equity Health

111

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IntroductionNon communicable diseases are the biggest cause of death worldwide. Beside mortality, these diseases also cause high rates of morbidity and disability. Their high prevalence is generally associated to multi-morbidity. Because they need costly prolonged treatment and care, non communicable diseases have social and economical consequences that affect individuals, households and the whole society. They raise the equity problem between and within countries.Methods and limitationsThis annotated bibliography is a systematic review on multimorbidy of non communicable diseases and health equity in WHO Eastern Mediterranean countries. Medline/PubMed, EMBASE and other sources were used to get peer reviewed papers dealing with the review theme. The words/strings used for search and inclusion criteria were: multimorbidity, comorbidity, equity, non communicable diseases, chronic diseases, WHO Eastern Mediterranean and Arab countries.Bibliography with annotationsAccording to the inclusion criteria, 26 papers were included in the present review. Generally, lack or paucity of publications was encountered in themes like headache, cancer and respiratory diseases. Of the 26 contributions selected, twelve dealt with comorbidity of depression and mental disorders with other chronic diseases. Another set of 11 publications was devoted to multimorbidity of diabetes, cardiovascular diseases (CVDs), hypertension, metabolic syndrome and obesity. Considering association of multimorbidity and social determinants, this review shows that female gender, low income, low level of education, old age and unemployed/retired are the most exposed to multimorbidity. It should also be stressed that, geographically, no contribution was issued from North African countries.Non communicable diseases are one of the biggest challenges facing health decision makers in WHO Eastern Mediterranean countries where the multidimensional transition is boosting increases in multimorbidity of depression and mental diseases, cardiovascular diseases, diabetes, cancer and respiratory diseases among the whole population but with the highest burden among the least disadvantaged individuals or subpopulations. Health ministries in WHO Eastern Mediterranean countries should pay a particular attention to the association between equity and multimorbidity and opt for cost effective strategies based on early diagnosis and sensitisation for healthy diet, physical activity, no smoking and no alcohol.

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Section: Bibliography With Annotationsmentioning

confidence: 99%

“…Patients treated in the ICU showed a worse prognosis for both patient and renal survival. Age, sex and ethnicity were the demographic data considered but no analysis was done [38]. …”

Section: Bibliography With Annotationsmentioning

confidence: 99%

Section: Bibliography With Annotationsmentioning

confidence: 99%

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Multi-morbidity of non communicable diseases and equity in WHO Eastern Mediterranean countries

Boutayeb

2013

Int J Equity Health

111

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“…In the prospective study mentioned earlier, drug-induced nephrotoxicity was a contributing factor identified in 19.0% of AKI patients (Uchino et al, 2005). Bernieh et al (2004) retrospectively evaluated 81 patients in a tertiary hospital reporting that in 11 patients (14%), the exposure to nephrotoxic drugs contributed to the occurrence of AKI. In the present study, age, race, number of comorbidities, length of ICU stay, number of drugs, S Cr level, GFR, and APACHE II score at hospital admission were the variables included in the final multiple logistic regression model, but only the number of drugs showed significant statistical association with AKI (OR 1.15; 95% CI 1.05-1.27).…”

Section: Discussionmentioning

confidence: 99%

“…Manuscript to be reviewed nephrotoxic drugs were reported to contribute to 14-21% of cases of AKI (Bernieh et al, 2004;Mehta et al, 2004;Uchino et al, 2005;KDIGO-AKI group, 2012). KDIGO guidelines have stated that rates may range from 20-30% (KDIGO-AKI group, 2012).…”

Section: Introductionmentioning

confidence: 99%

Peer Review #1 of "Drug therapy and other factors associated with the development of acute kidney injury in critically ill patients: a cross-sectional study (v0.2)"

Silva¹

2018

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Background: Acute kidney injury (AKI) is associated with a significant increase in morbidity, mortality, and health care costs. In intensive care units (ICU), AKI is commonly multifactorial and frequently involves diverse factors, such as hypovolemia, sepsis, and the use of nephrotoxic drugs. We aimed to investigate drug therapy and other factors associated with the development of AKI in a Brazilian public hospital. Methods: This is a cross-sectional study involving critically ill patients at an ICU of a tertiary hospital. All data on sequential serum creatinine (S Cr) level, glomerular filtration rate (GFR), and urine output were collected during ICU stay. The primary outcome was the occurrence of AKI assessed by the Acute Kidney Injury Network (AKIN) criterion. Sociodemographics, clinical data and drug therapy were considered as covariates. Factors associated with AKI were assessed using logistic regression. Results: Overall, 122 participants were included in the study. Median age was 46.0 (interquartile range, IQ=29.0-69.0) years, with a predominance of men (58.2%). Mean number of prescribed drugs throughout ICU stay was 22.0±9.4. The number of potentially nephrotoxic drugs ranged from 2-24 per patient. A total of 29 (23.8%) ICU patients developed AKI. In the AKI-group, patients were older and showed higher Acute Physiology and Chronic Health Evaluation II (APACHE II) score at admission, higher rates of sedation, mechanical ventilation, and infection. More drugs in general and specifically more vasoactive drugs were prescribed for AKI group. Patients who developed AKI tended to have extended stays in the ICU and a lower probability of being discharged alive than patients with no AKI development. Model adjustments of logistic regression showed that the number of medications (OR 1.15; 95% CI 1.05-1.27) was the only factor associated with AKI in this study. This association was independent of drug nephrotoxicity. Discussion: Intensive care is characterized by its complexity that combines unstable patients, severe diseases, high density of medical interventions, and drug use. We found

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Nephrology in the United Arab Emirates

Alrukhaimi

Ismaili

Alobaidli

2021

Nephrology Worldwide

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Pattern of acute renal failure in a tertiary hospital in the United Arab Emirates

Cited by 15 publications

References 18 publications

Multi-morbidity of non communicable diseases and equity in WHO Eastern Mediterranean countries

Multi-morbidity of non communicable diseases and equity in WHO Eastern Mediterranean countries

Peer Review #1 of "Drug therapy and other factors associated with the development of acute kidney injury in critically ill patients: a cross-sectional study (v0.2)"

Nephrology in the United Arab Emirates

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