Pattern of antibiotic use in neonatal intensive care unit in tertiary care hospital in Southern India

Shinde, Anjali R.; Bairagi, Jaydeep M.; Khanwelkar, Chitra C.; Shinde, Ravindra V.; Mohite, Vaishali R.

doi:10.18203/2319-2003.ijbcp20162473

Cited by 4 publications

(3 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, in the majority of circumstances, either culture or sensitivity testing are not performed, or antibiotics are continued for extended periods of time despite the fact that the organisms are not sensitive. 7 Prescription pattern studies are required to ensure safe and effective medication usage at all stages of therapy, which aids in identifying inappropriate types of prescribing such as polypharmacy and irrational use of antimicrobials and injectables. It is also necessary to describe trends and ensure that various treatment guidelines are followed.…”

Section: Introductionmentioning

confidence: 99%

Study of Drug Prescribing Pattern in Pediatric Outpatient Department at a Tertiary Care Teaching Hospital

Rahul¹,

Sravya²,

Hiremath³

2021

J. Drug Delivery Ther.

View full text Add to dashboard Cite

Background: Infants and children suffer from frequent but usually non serious illnesses and are more vulnerable to various adverse events related to drugs and poor understanding of instructions on prescription by the patient or caretakers were likely to cause medication error. The correct identification of an illness and its management with medications is a vital aspect of patient care, especially for paediatric population. So, prescribing pattern studies are very helpful in promoting the appropriate use of drugs in population. Objectives: It aims to obtain data on the current prescribing pattern in pediatric OPD at a tertiary care teaching hospital with ultimate goal to promote appropriate use of drugs. Methods: This study was conducted in 62 pediatric patients of either sex visiting Pediatric out-patient department over a period of three months at NMCH and RC, Raichur, Karnataka. Results: Prescription analysis showed that the average number of drugs per prescription was 3.32. Drugs were mostly prescribed by brand name (98.06%), Injections (4.83%) were least prescribed, drugs prescribed from Essential Drug List was 48.54%. Antibiotics were most prescribed class of drugs (33.9%). Conclusion: The study concludes that polypharmacy was slightly seen in prescriptions. Diagnosis of the patient was recorded for most of the prescriptions. There is need to conduct many such studies at regular interval as it is useful for auditing large number of prescriptions to find out early signals of the irrational drug use. Our study evaluated drug use pattern only from the outpatients hence prescription pattern may vary among inpatients. Keywords: Prescribing pattern, Infants, WHO core prescribing indicators, Polypharmacy, Generic name

show abstract

Section: Introductionmentioning

confidence: 99%

Study of Drug Prescribing Pattern in Pediatric Outpatient Department at a Tertiary Care Teaching Hospital

Rahul¹,

Sravya²,

Hiremath³

2021

J. Drug Delivery Ther.

View full text Add to dashboard Cite

show abstract

“…The mean age observed in both retrospective and prospective study was comparatively lower than the previous studies done by Athawale et Our study showed that the most common cause of patients getting admitted in MICU was infective diseases in both retrospective and prospective arm contributing by 71% and 67% respectively which is similar to study done by Maharani et al and it was in contrast to other studies such as Patanaik et al which showed cerebrovascular accident as most common cause (20.5%) of admission and Shobha et al which showed respiratory causes as most common cause (21.7%). 2,4,5 Higher incidence of infective diseases in our studies may be attributed to study period which was from June to December which is a period of rainy season contributing to many vector-borne diseases such as dengue, malaria, leptospirosis. This may be the reason of higher number of infective diseases in our study.…”

Section: Discussionmentioning

confidence: 76%

A study comparing the change in drug utilization pattern in medical intensive care unit of a tertiary care hospital in seven years

Karve,

Chaure

2023

Int J Basic Clin Pharmacol

View full text Add to dashboard Cite

Background: Medical intensive care unit is a type of intensive care unit that takes care of a range of medical illnesses with patients who are seriously ill and/or suffer from severe chronic illnesses. These patients are usually prescribed multiple drugs. Use of antimicrobial agents and injectable medications in setting of MICU is high as compared with other class of drugs and other hospital settings respectively. Periodic evaluation of drug utilization pattern needs to be done to enable suitable modifications in prescription of drugs to increase the therapeutic benefit and decrease the adverse effects. There could be changes in drug utilization pattern due to changes in disease pattern, development of newer drugs, resistance to antimicrobial agents. Hence comparison of past and present data needs to be done to find out the changes that occurred in drug utilization pattern over the years. Methods: Data was collected from June 2021 to Dec 2021 for prospective arm and June 2014 to December 2014 for retrospective arm was obtained from MICU of tertiary care hospital and Medical Record Department. Drug utilization pattern was analysed and compared with appropriate statistical tests. Results: Most common cause of MICU admission was infective diseases (71% and 67% respectively in retrospective and prospective arm). The drug prescribed frequently was pantoprazole and antimicrobial was ceftriaxone in both the study arms. Half of the drugs were prescribed by generic names in both arms. Conclusions: There was no change observed in drug utilization pattern and disease pattern in patients admitted to medical intensive care unit over the years in our institute.

show abstract

“…This is because their physiological functions are immature leading to high morbidity and mortality. 5 Major neonatal mortality and morbidity worldwide is due to septicemia comprising various systemic infections of the newborn such as septic shock, meningitis, pneumonia, arthritis, osteomyelitis, and urinary tract infections. 6 Empirical antibiotic therapy needs to be given immediately on suspicion of septicemia followed by cultures and sensitivity, later based on report reevaluation of antibiotic treatment provided can be done.…”

Section: Introductionmentioning

confidence: 99%

Prescription pattern of antibiotics in neonatal intensive care unit of tertiary care hospital

Baig

Naikwadi

Deshmukh

2019

Int J Basic Clin Pharmacol

View full text Add to dashboard Cite

Background: Recurrent and prolonged courses of antibiotics exposure have resulted in an increase in the prevalence of hospital acquired infections and antibiotic resistant profile. The objective of this study was to quantify the use of antibiotics in a neonatal intensive care unit (NICU) of Govt. Medical College and Hospital, Aurangabad, Maharashtra, a tertiary health care centre.Methods: A total of 260 neonates admitted in NICU from August 2017 to February 2018 were enrolled in the study and fulfilling inclusion criteria of the study. Demographic details, data on antibiotic prescriptions (name, dose, frequency, route of administration) was recorded on pre-tested structured Performa.Results: A total of 248 neonates received the antibiotics. EOS pneumonia was most common i.e. 29.8% followed by LOS pneumonia (20.6%). Sepsis, pneumonia Meningitis, NEC, were common indications for admission in NICU. Among the antibiotic combinations amoxicillin + clavulanate (38.99%), was most commonly prescribed followed by gentamicin (37.89%) and piperacillin (11.01%) respectively. Other antibiotics like, linezolide (0.94%), fluconazole (5.97%), meropenem (4.42%), vancomycine (0.77%) were also used less commonly in NICU. About fifty of the medicine prescribed were in compliance with the national list of essential medicines 2011.Conclusions: In tertiary care setup of NICU amoxicillin + clavulanate and gentamicin are most commonly used antibiotics in NICU. The study concludes that the antibiotic prescription pattern at NICU of our tertiary care hospital was found rational.

show abstract

Pattern of antibiotic use in neonatal intensive care unit in tertiary care hospital in Southern India

Cited by 4 publications

References 12 publications

Study of Drug Prescribing Pattern in Pediatric Outpatient Department at a Tertiary Care Teaching Hospital

Study of Drug Prescribing Pattern in Pediatric Outpatient Department at a Tertiary Care Teaching Hospital

A study comparing the change in drug utilization pattern in medical intensive care unit of a tertiary care hospital in seven years

Prescription pattern of antibiotics in neonatal intensive care unit of tertiary care hospital

Contact Info

Product

Resources

About