Pattern of Candida Species Isolated from Patient with Vulvovaginal Candidiasis in Pregnancy

Abstract

Background: Vulvovaginal candidiasis (VVC) is one of the most prevalent genital tract diseases in women. The identification of the isolated Candida species is critical for guiding empirical antifungal therapy. Purpose: To determine the Candida species that cause vulvovaginal candidiasis in pregnancy at the Obstetrics and Gynecology Outpatient Clinic, Dr. Soetomo General Academic Hospital, thus providing scientific and therapeutic benefits. Methods: Pregnant woman receiving antenatal care (ANC) at Dr. Soetomo General Academic Hospital Obstetric and Gynecology Outpatient Clinic. Subjects were enrolled in a cross-sectional study during 3 months between March and May 2021. Vaginal swab samples were taken from subjects after informed consent. A specific color change in CHROMagar cultures and VITEK 2 compact were used to identify Candida species. Result: During the study period, 15 pregnant patients were diagnosed with VVC. The majority of the women in the study were pregnant women of sexually active age who complained of a whitish body and genital irritation. There were 18 candida isolates from CHROMagar cultures, with C. non albicans (61.1%) predominating over C. albicans (38.3%). With details, non albicans were C. glabrata (54.4%), C. dubliniensis (36.3%), and C. parapsilosis (18.1%). Conclusion: This study revealed a high prevalence of Candida non-albicans species causing VVC. Culture investigation and identification of Candida are critical to avoid diminished susceptibility to antifungal treatments and recurrence.

Isolasi Candida albicans pada Urine Ibu Hamil dengan Media Sabouraud Dextrose Agar (SDA) Masa Pandemi Covid-19

“…Pada masa pandemi covid-19, wanita hamil lebih beresiko mengalami Fluor albus patologis, serta mudah terinfeksi apabila tidak memperhatikan personal hygiene yang baik sehingga berpengaruh pada penurunan respon imun. Pada penelitian terdahulu yang dilakukan di India di tahun 2012, diperoleh hasil yaitu insidensi kandidiasis vaginalis meningkat di wanita hamil sebanyak 22,5% dibandingkan dengan wanita yang tidak hamil sebanyak 16,66% (Aring et al, 2012;Purnamasari et al, 2022).…”