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Background: Severe community-acquired pneumonia (SCAP) represents a frequent and potentially life-threatening condition. About 10% of all hospitalized patients with CAP require admission to the intensive care unit (ICU), and the mortality of these patients reaches 20-50%.Objective: To evaluate the clinical presentation, bacteriological profile and outcome of severe community-acquired pneumonia (SCAP).Patients and methods: 54 patients presented by symptoms and sign of severe community acquired pneumonia who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital from August 2015 to March 2016 were subjected to full clinical examination, chest X ray, complete blood picture, sputum and blood culture, PCR for suspected cases of Influenza H1N1 and MERS-COV, treatment, follow up, data collections and statistical analysis.Results: The present study included 54 patients 26 males and 28 females with SCAP who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital. The most common comorbidities were diabetes mellitus and hypertension. The most common presentations were fever, cough, dyspnea and hypoxemia. Two patients developed renal failure and 4 patients developed septic shock. The most common isolated organism was Streptococcus pneumoniae, Influenza H1N1, and Staphylococcus aureus. Mortality was 24% and it was common in patients with comorbidity than in patients without comorbidities.Conclusion: SCAP occurs more frequently in those with comorbidities. The most frequent isolated causative organism of SCAP is S. pneumoniae, Influenza H1N1 and S. aureus. SCAP is associated with significant mortality, early recognition and prompt treatment may improve outcome.
Background: Severe community-acquired pneumonia (SCAP) represents a frequent and potentially life-threatening condition. About 10% of all hospitalized patients with CAP require admission to the intensive care unit (ICU), and the mortality of these patients reaches 20-50%.Objective: To evaluate the clinical presentation, bacteriological profile and outcome of severe community-acquired pneumonia (SCAP).Patients and methods: 54 patients presented by symptoms and sign of severe community acquired pneumonia who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital from August 2015 to March 2016 were subjected to full clinical examination, chest X ray, complete blood picture, sputum and blood culture, PCR for suspected cases of Influenza H1N1 and MERS-COV, treatment, follow up, data collections and statistical analysis.Results: The present study included 54 patients 26 males and 28 females with SCAP who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital. The most common comorbidities were diabetes mellitus and hypertension. The most common presentations were fever, cough, dyspnea and hypoxemia. Two patients developed renal failure and 4 patients developed septic shock. The most common isolated organism was Streptococcus pneumoniae, Influenza H1N1, and Staphylococcus aureus. Mortality was 24% and it was common in patients with comorbidity than in patients without comorbidities.Conclusion: SCAP occurs more frequently in those with comorbidities. The most frequent isolated causative organism of SCAP is S. pneumoniae, Influenza H1N1 and S. aureus. SCAP is associated with significant mortality, early recognition and prompt treatment may improve outcome.
Background Community-acquired pneumonia (CAP), a prevalent lower respiratory tract infection, poses a significant health and economic burden. This study explores the clinical and economic implications of CAP among adults in diverse medical centers in India, emphasizing the need for a comprehensive understanding of its impact. Methods A cross-sectional multicenter survey, employing the CAP-Burden of Illness Questionnaire, was conducted among newly diagnosed severe CAP patients treated in seven participating medical centers. Both inpatient and outpatient cohorts were included, and data on symptoms, comorbidities, treatment patterns, and resource utilization were collected. The study involved 188 patients, and statistical analyses were performed using SPSS® (version 22) statistical software. Results The CAP-Burden of Illness Questionnaire revealed the persistence of symptoms, impacting daily life and work productivity. Hospitalized patients faced longer recovery times and increased resource utilization. As per the pulmonologists, the hospitalized patients in a private setting had an average length of stay (LOS) of 9 days in the ICU and 5 days in the general ward, whereas at the government hospital, the average LOS in the ICU was an average of 30 days and 8.5 days in the general ward. Average inpatient costs were INR 2,10,862 per patient in private hospitals and INR 5,575 per patient in government hospitals. Non-hospitalized patients reported an average outpatient treatment cost of INR 4,121 per patient in private settings and INR 200 per patient in government hospitals. Conclusion The economic analysis sheds light on the disparities in treatment costs, emphasizing the importance of considering healthcare settings. Addressing the multifaceted challenges of CAP requires a holistic approach, encompassing preventive measures, early detection, and targeted management strategies.
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