Pattern of drug prescription for the treatment of falciparum malaria in a medical college in Eastern India

Datta, Pratyay Pratim; Prasad, Anju; Pattanayak, Chaitali; Chouhan, Ashok Singh; Panda, Parbaty

doi:10.3126/ajms.v7i4.14614

Cited by 2 publications

(9 citation statements)

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“…18 15,20 Two other studies from India reported use of primaquine which varied from 12.5% to 56.7%. 16,18 In the present study the average number of drugs per prescription was 3.79 in children and 3.59 in adults. According to World Health Organization guideline of rational use of medicine, the average number of drug per prescription should be 1.6-1.8.…”

Section: Resultsmentioning

confidence: 40%

“…In one study from a tertiary care hospital in Eastern India showed that artesunate (48.1%) and mefloquine (25.9%) were the most common antimalarials for falciparum malaria. 16 In another study from Karnataka reported quinine and artesunate mono-therapy in respectively 80% and 5% of falciparum malaria cases. 18 15,20 Two other studies from India reported use of primaquine which varied from 12.5% to 56.7%.…”

Section: Resultsmentioning

confidence: 97%

“…18 Another study from a tertiary care center in Odisha reported that chloroquine was prescribed to 23.1% of P. falciparum patients. 16 Anti-malarial drug utilization studies in Nigeria in 2003 and 2004 reported use of chloroquine in 30.2% and 47% of P. vivax patients respectively. 12,19 In studies in tertiary care set-ups in Karnataka and Uttar Pradesh, chloroquine mono-therapy was done in 60.37% and 18.51% respectively.…”

Section: Resultsmentioning

confidence: 99%

“…19 In studies in Odisha and Karnataka reported respectively 43.3% and 9.45% encounters with antibiotics. 16,18 Other than anti-malarials, paracetamol was the most commonly prescribed drug in both children (26.37%) and in adults (17.53%), pantoprazole being the second commonest drug prescribed (9.11%) in adults only. One study from Odisha reported that proton pump inhibitors (65.4%) were the commonest co-prescribing other drug group.…”

Section: Resultsmentioning

confidence: 99%

“…15 Another study from Odisha highlighted the anti-malarial use pattern in a tertiary care set-up. 16 Malaria and other vector-borne diseases situation in Kolkata Municipal Corporation areas were analyzed in different studies, though anti-malarial use pattern was not assessed by researchers. 7,17 This study pioneers to analyze the antimalarial prescribing practices from a tertiary care Medical College and Hospital in Kolkata, West Bengal.…”

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confidence: 99%

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Assessment of anti-malarial drug prescribing pattern in pediatric and adult malaria patients in a tertiary care hospital in Eastern India

Mandal

Sarkar

et al. 2019

Int J Adv Med

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Background: Kolkata, one of the major metropolitan cities of India, is also the capital of the state West Bengal, contributes largest number of malaria cases reported from West Bengal. The present study was undertaken to assess the anti-malarial prescribing pattern in a tertiary care teaching hospital in Kolkata.Methods: This was an observational, prospective, cross-sectional study for a period of one year (from March 2017 to February 2018) in which prescriptions of diagnosed pediatric and adult malaria patients were scanned and reviewed for anti-malarial use pattern. Core drug use indicators were also analyzed to assess the rational prescribing pattern.Results: During one-year study period, 122 adult and 24 child malaria patient encounters were screened. Among adult patients, 48(39.3%) patients had P. falciparum and 74(60.7%) patients had P. vivax malaria; in children, 9(37.5%) patients had P. falciparum and 15(62.5%) patients had P. vivax malaria. All adult and pediatric P. vivax malaria patients were treated with chloroquine. Artemisinin derivatives were prescribed to 91.67% of adult and 88.88% of pediatric falciparum malaria patients, 77.09% of adults and 66.67% of children received ACT. Artemether- lumefantrine was the most commonly prescribed ACT (33.34% in adults and 55.56% in children). Prescriptions were usually in generic name and from National EDL. Percentage of encounters with antibiotics was high in both age group but percentage of encounters with injections was low in adults and children. Conclusion: Chloroquine was used rationally for treatment of P. vivax malaria patients. Artemether-lumefantrine was the most common ACT used for treatment of P.falciparum malaria cases though the National guideline for treatment of malaria does not recommend Artemether-lumefantrine for this state and region for treatment of falciprum cases.

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Section: Resultsmentioning

confidence: 40%

Section: Resultsmentioning

confidence: 97%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

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Assessment of anti-malarial drug prescribing pattern in pediatric and adult malaria patients in a tertiary care hospital in Eastern India

Mandal

Sarkar

et al. 2019

Int J Adv Med

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Prescribing trend of treating malaria patients by public and private healthcare facilities in Lahore

Goher,

Hameed Khaliq,

Waleed Yousaf

2022

Bull Pharm Med Res

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Malaria is an infectious disease caused by parasites of the Plasmodium genus. It is one of the major causes of morbidity and mortality worldwide. The World Health Organization (WHO) has recommended artemisinin combination therapy (ACT) to manage malaria among children and adults. However, chloroquine as monotherapy and ACT are commonly prescribed in treating malaria in Pakistan's healthcare delivery system. Therefore, this study assessed the prescribing trends for treating malaria patients in public and private healthcare facilities. Moreover, the study also determined the number of drugs prescribed per prescription by physicians and consultants. This descriptive study was conducted for six months in Lahore's major public and private healthcare facilities. A purposive sampling technique was employed to review 300 malaria patients' prescriptions accessed from the hospital records. Descriptive statistics and the chi-square test were used to achieve the study's objectives. The study showed that most malaria prescriptions were from both public (64.67%) and private healthcare facilities (42.67%) and comprised a dual-drug regimen involving antimalarials, antibiotics, antipyretics, or their combinations. There was a significant difference (p = 0.002) in the prescription trend between public and private healthcare facilities regarding the number of drugs prescribed for treating malaria. Moreover, prescriptions from private healthcare facilities mainly contained antimalarial drugs (58.59%) and antibiotics (17.60%), while most prescriptions from public healthcare facilities contained antipyretics and other drugs (60.67%) (p = 0.001). Most of the consultants prescribed two (66.67%) or three drugs (33.33%), while the prescribing trends of physicians ranged between one and four, which was also statistically significantly different (p = 0.001). In addition, most prescriptions from public healthcare facilities were rationally prescribed (68%). On the other hand, most prescriptions from private healthcare facilities were rational (54%) and semirational (42%). The rationality of prescriptions by public and private healthcare facilities was also significantly different (p = 0.001). Public healthcare facilities were found to exhibit more rational prescribing trends for managing malaria compared to private healthcare facilities, with a focus on prescribing an optimal number of drugs per prescription and a lower usage of antimalarial and antibiotic medications.

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Pattern of drug prescription for the treatment of falciparum malaria in a medical college in Eastern India

Cited by 2 publications

References 3 publications

Assessment of anti-malarial drug prescribing pattern in pediatric and adult malaria patients in a tertiary care hospital in Eastern India

Assessment of anti-malarial drug prescribing pattern in pediatric and adult malaria patients in a tertiary care hospital in Eastern India

Prescribing trend of treating malaria patients by public and private healthcare facilities in Lahore

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