Pattern of Dyslipidemia in different type of Myocardial Infarction

Abstract

Background: Dyslipidemia is one of the main risk factors with prognostic significance in relation to coronary heart disease. Aggressive treatment has been recommended in acute coronary syndrome (ACS). We examined pattern of dyslipidemia in ST Elevation myocardial infarction (STEMI) and Non- ST elevation myocardial infarction (NSTEMI). We also compare the lipid status in between two types of myocardial infarction (MI).Methods: This cross sectional observational study was carried out enrolling 100 subjects with ST elevation and Non ST elevation Myocardial Infarction, in the Department of Cardiology, BIRDEM General Hospital, Shahbag, Dhaka, over a period of six months from January 2012 to June 2012. Fasting lipid profile was done in next morning of admission in both type of MI.Results: Mean age and gender difference was significant between STEMI and NSTEMI. Mean Cholesterol (chol), Triglyceride (TG), high density lipoprotein (HDL) and low density lipoprotein (LDL) were not statistically significant between male and female groups. All mean cholesterol, TG, HDL, LDL were significantly high in older age group. The Mean cholesterol (220.7±28.1Vs208.4±20.9), triglyceride (182.8±34.4 Vs 147.4±28.9), HDL (35.14±5.7 Vs 41.65±3.8) and LDL (160.7±26.2 Vs148.3±16.8)were also statistically significant between STEMI and NSTEMI groups (p<0.05).Conclusion: Dyslipidemia is the dominating coronary risk factors. It could be concluded that significant differences are observed between two types of MI. Lipid status is relatively more uncontrolled in ST elevated MI and must be managed with all possible therapeutic modules to minimize further complications.Bangladesh Crit Care J September 2017; 5(2): 106-109

Triglyceride to High Density Lipoprotein Cholesterol Ratio in Acute Myocardial Infarction And Its Relationship with Angiographic Severity

“…Similar sex ratio with male predominance were also observed by other studies. [10][11][12] Regarding the traditional risk factors, it was found in the current study that, most of the patients of AMI (211/224; 94.2%) had unrecognized dyslipidemia. Similar to this finding reported such high prevalence (85.1% and 82.1% respectively) of unrecognized dyslipidemia among the admitted patients for first time AMI.…”

“…Previous studies from Bangladesh reported similar age distribution of patients with AMI with mean age around 51 years with maximum number of the patients in the age range of 51-60 years. [10][11][12] In contrast to these findings from Bangladesh, studies from India reported comparatively higher mean age like 62.74 ± 13.6 years, 13 56.06 ± 11.29 years,14 and 56.75 ± 10.47 years. 15 Moreover, western study has reported higher mean age as compared to these studies conducted in Asia such as study (68 years).…”

“…The prevalence of high TG (28-72.2%), high LDL cholesterol (23.3-44.5%), low HDL (27-72.2%) and high TC (19-38.7%) were observed from different region of India and Bangladesh. 10,11,21 These variations can be explained by differences in the study population with respect to age and sex distribution, inclusion of patients with CVD and population or hospital-based study.…”

“…9 Several studies have reported the condition of dyslipidemia among CAD patients of Bangladesh but the study assessing association between TG to HDL-C ratio and severity of CAG findings among MI patients. [10][11] There are few studies on TG/HDL-C ratio in AMI and their Angiographic correlation in Bangladesh. The relevance of this study is to correlate relationship of TG/HDL-C in AMI and to see their angiographic severity.…”